ENSDARG00000014722


Danio rerio

Features
Gene ID: ENSDARG00000014722
  
Biological name :her1
  
Synonyms : hairy-related 1 / her1
  
Possible biological names infered from orthology : HES7 / hes family bHLH transcription factor 7 / Q8BKT2 / Q9BYE0 / Transcription factor HES-7
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 68788658
Gene end: 68795063
  
Corresponding Affymetrix probe sets: Dr.1462.1.S1_at (Zebrafish Array)   NM_131078_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000027076
NCBI entrez gene - 30287     See in Manteia.
RefSeq - NM_131078
RefSeq Peptide - NP_571153
swissprot - A3KQ56
ZFIN ID - ZDB-GENE-980526-125
Ensembl - ENSDARG00000014722
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HES7ENSG00000179111Homo sapiens
 Hes7ENSMUSG00000023781Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
her11 / hairy-related 11 / HES7* / Q9BYE0* / Q8BKT2* / Transcription factor HES-7 * / hes family bHLH transcription factor 7*ENSDARG0000000270723
her5 / hairy-related 5ENSDARG0000000879616


Protein motifs (from Interpro)
Interpro ID Name
 IPR003650  Orange domain
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001756 somitogenesis IMP
 biological_processGO:0001757 somite specification IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IPI
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IC
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000072 somite 1 somite 1 somite border amorphous , abnormal
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 ZFA:0000073 somite 5 somite 5 somite border amorphous , abnormal
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 ZFA:0000155 somite somite quality , abnormal
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 ZFA:0000728 somite 2 somite 2 somite border amorphous , abnormal
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 ZFA:0000732 somite 3 somite 3 somite border amorphous , abnormal
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 ZFA:0000733 somite 7 somite 7 somite border amorphous , abnormal
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 ZFA:0000857 somite 4 somite 4 somite border amorphous , abnormal
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 ZFA:0000858 somite 8 somite 8 somite border amorphous , abnormal
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 ZFA:0000974 somite 10 somite 10 somite border amorphous , abnormal
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 ZFA:0000982 somite 6 somite 6 somite border amorphous , abnormal
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 ZFA:0000983 somite 9 somite 9 somite border amorphous , abnormal
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 ZFA:0001056 myotome myotome morphology , abnormal
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 ZFA:0001462 somite border somite border absent , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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