ENSDARG00000017121


Danio rerio

Features
Gene ID: ENSDARG00000017121
  
Biological name :mafba
  
Synonyms : mafba / Q98UK5 / v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
  
Possible biological names infered from orthology : MAFB / MAF bZIP transcription factor B / P54841 / Q9Y5Q3 / Transcription factor MafB
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 3405665
Gene end: 3409140
  
Corresponding Affymetrix probe sets: Dr.608.1.A1_at (Zebrafish Array)   NM_131015_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000018087
Ensembl peptide - ENSDARP00000152024
NCBI entrez gene - 30210     See in Manteia.
RefSeq - NM_131015
RefSeq Peptide - NP_571090
swissprot - Q98UK5
ZFIN ID - ZDB-GENE-980526-515
Ensembl - ENSDARG00000017121
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAFBENSGALG00000003670Gallus gallus
 MAFBENSG00000204103Homo sapiens
 MafbENSMUSG00000074622Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mafb / v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog b (paralog b) / MAF* / O75444* / P54843* / Transcription factor Maf * / MAF bZIP transcription factor*ENSDARG0000007652049
mafa / v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a) / MAF* / O75444* / P54843* / Transcription factor Maf * / MAF bZIP transcription factor*ENSDARG0000001589048
mafaa / A3KMR8 / v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa / MAFA* / Q8CF90* / Q8NHW3* / Transcription factor MafA * / MAF bZIP transcription factor A*ENSDARG0000004415544
mafbb / v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb / MAFB* / P54841* / Q9Y5Q3* / Transcription factor MafB * / MAF bZIP transcription factor B*ENSDARG0000007054241
nrl / neural retina leucine zipper / P54845*ENSDARG0000010046633
mafk / v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K / O60675* / Q61827* / MAF bZIP transcription factor K* / v-maf musculoaponeurotic fibrosarcoma oncogene family, protein...ENSDARG0000010094717
mafga / v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ga / MAFG* / O15525* / O54790* / Transcription factor MafG * / MAF bZIP transcription factor G*ENSDARG0000001810916
mafgb / v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb / MAFG* / O15525* / O54790* / Transcription factor MafG * / MAF bZIP transcription factor G*ENSDARG0000010009716
maff / v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F / O54791* / Q9ULX9* / Transcription factor MafF * / MAF bZIP transcription factor F*ENSDARG0000002895714


Protein motifs (from Interpro)
Interpro ID Name
 IPR004826  Basic leucine zipper domain, Maf-type
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR013592  Maf transcription factor, N-terminal
 IPR024874  Transcription factor Maf family
 IPR028571  Transcription factor MafB


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001946 lymphangiogenesis IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated ISS
 biological_processGO:0009880 embryonic pattern specification IMP
 biological_processGO:0009952 anterior/posterior pattern specification IMP
 biological_processGO:0021571 rhombomere 5 development IMP
 biological_processGO:0021572 rhombomere 6 development IMP
 biological_processGO:0021654 rhombomere boundary formation IMP
 biological_processGO:0039021 pronephric glomerulus development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain morphology , abnormal
hindbrain radial glial cell disorganized , abnormal
hindbrain decreased length , abnormal
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 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
otic vesicle morphology , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000069 rhombomere 6 rhombomere 6 aplastic , abnormal
rhombomere 6 decreased size , abnormal
rhombomere 6 anterior/posterior compartment boundary absent , abnormal
rhombomere 6 rhombomere boundary formation arrested , abnormal
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 ZFA:0000217 inner ear inner ear quality , abnormal
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 ZFA:0000282 sensory system sensory system quality , abnormal
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 ZFA:0000477 posterior cardinal vein posterior cardinal vein endothelial cell increased amount , abnormal
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 ZFA:0000530 lapillus lapillus fused with sagitta , abnormal
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 ZFA:0000671 horizontal myoseptum horizontal myoseptum lymphangioblast morphology , abnormal
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 ZFA:0000713 abducens motor nucleus abducens motor nucleus absent , abnormal
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 ZFA:0000823 rhombomere 5 rhombomere 5 morphology , abnormal
rhombomere 5 aplastic , abnormal
rhombomere 5 decreased size , abnormal
rhombomere 5 anterior/posterior compartment boundary absent , abnormal
rhombomere 5 rhombomere boundary formation arrested , abnormal
Show

 ZFA:0000949 rhombomere 7 rhombomere 7 anterior/posterior compartment boundary absent , abnormal
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 ZFA:0001064 rhombomere rhombomere primary neuron disorganized , abnormal
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 ZFA:0001094 whole organism whole organism edematous , abnormal
whole organism decreased pigmentation , abnormal
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 ZFA:0001306 pharyngeal arch pharyngeal arch cartilage element malformed , abnormal
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 ZFA:0001557 pronephric glomerulus pronephric glomerulus cystic , abnormal
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 ZFA:0001606 pharyngeal arch 3 pharyngeal arch 3 cartilage element increased thickness , abnormal
pharyngeal arch 3 cartilage element truncated , abnormal
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 ZFA:0001692 hindbrain commissure hindbrain commissure axon decussate , abnormal
hindbrain commissure neuron decreased amount , abnormal
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 ZFA:0005105 lymph vasculature lymph vasculature hypoplastic , abnormal
lymph vasculature aplastic , abnormal
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 ZFA:0005110 thoracic duct thoracic duct absent , abnormal
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 ZFA:0005319 intersegmental lymph vessel intersegmental lymph vessel absent , abnormal
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 ZFA:0005320 dorsal longitudinal lymphatic vessel dorsal longitudinal lymphatic vessel absent , abnormal
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 ZFA:0005832 lymphatic branchial arch 1 lymphatic branchial arch 1 endothelial cell decreased amount , abnormal
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 ZFA:0005837 lateral facial lymph vessel lateral facial lymph vessel endothelial cell decreased amount , abnormal
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 ZFA:0005838 otolithic lymph vessel otolithic lymph vessel endothelial cell decreased amount , abnormal
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 ZFA:0005839 medial facial lymph vessel medial facial lymph vessel endothelial cell decreased amount , abnormal
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 ZFA:0005844 lymph vessel lymph vessel endothelial cell decreased amount , abnormal
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 ZFA:0007063 neural crest hindbrain neural crest hindbrain neural crest cell migration process quality , abnormal
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 ZFA:0009044 blood cell blood cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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