ENSDARG00000018334


Danio rerio

Features
Gene ID: ENSDARG00000018334
  
Biological name :rpl35
  
Synonyms : Q8JHJ1 / ribosomal protein L35 / rpl35
  
Possible biological names infered from orthology : 60S ribosomal protein L35 / Gm10269 / Gm2000 / P42766 / predicted gene 2000 / Q6ZWV7
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 5873227
Gene end: 5881344
  
Corresponding Affymetrix probe sets: Dr.5098.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000018594
Ensembl peptide - ENSDARP00000151606
NCBI entrez gene - 192299     See in Manteia.
swissprot - Q8JHJ1
ZFIN ID - ZDB-GENE-020419-2
Ensembl - ENSDARG00000018334
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPL35ENSGALG00000035677Gallus gallus
 RPL35ENSG00000136942Homo sapiens
 Gm10269ENSMUSG00000091449Mus musculus
 Gm2000ENSMUSG00000078193Mus musculus
 Rpl35ENSMUSG00000062997Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001854  Ribosomal protein L29/L35
 IPR018254  Ribosomal protein L29, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0006412 translation IBA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030218 erythrocyte differentiation IMP
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0051726 regulation of cell cycle IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit IBA
 molecular_functionGO:0003729 mRNA binding IBA
 molecular_functionGO:0003735 structural constituent of ribosome IBA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
SRP-dependent cotranslational protein targeting to membrane
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000006 ball ball increased size , abnormal
ball opaque , abnormal
Show

 ZFA:0000008 brain brain aplastic , abnormal
brain quality , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000029 hindbrain hindbrain undulate , abnormal
hindbrain quality , abnormal
Show

 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary decreased thickness , abnormal
Show

 ZFA:0000084 yolk yolk circular , abnormal
Show

 ZFA:0000106 extension extension decreased length , abnormal
extension decreased thickness , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000108 fin fin aplastic , abnormal
Show

 ZFA:0000109 forebrain forebrain protruding , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle increased size , abnormal
fourth ventricle distended , abnormal
Show

 ZFA:0000138 otic placode otic placode decreased size , abnormal
otic placode aplastic , abnormal
Show

 ZFA:0000142 peripheral nervous system peripheral nervous system nerve neoplastic , abnormal
peripheral nervous system chromosome amount , abnormal
Show

 ZFA:0000152 retina retina decreased size , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0000445 optic tectum optic tectum increased size , abnormal
optic tectum opaque , abnormal
Show

 ZFA:0000559 otolith organ otolith organ deformed , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism decreased size , abnormal
whole organism viability , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk decreased thickness , abnormal
Show

 ZFA:0001117 post-vent region post-vent region deformed , abnormal
post-vent region bent , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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