ENSDARG00000020197


Danio rerio

Features
Gene ID: ENSDARG00000020197
  
Biological name :rpl5a
  
Synonyms : ribosomal protein L5a / rpl5a
  
Possible biological names infered from orthology : P46777 / P47962 / ribosomal protein L5 / RPL5
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 10687276
Gene end: 10703621
  
Corresponding Affymetrix probe sets: Dr.876.1.S1_at (Zebrafish Array)   NM_199756_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000006085
NCBI entrez gene - 326961     See in Manteia.
RefSeq - NM_199756
RefSeq Peptide - NP_956050
swissprot - Q7ZUI0
ZFIN ID - ZDB-GENE-030131-5161
Ensembl - ENSDARG00000020197
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPL5ENSGALG00000005922Gallus gallus
 RPL5ENSG00000122406Homo sapiens
 Rpl5ENSMUSG00000058558Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rpl5b / ribosomal protein L5b / RPL5* / P46777* / P47962* / ribosomal protein L5*ENSDARG0000001586292


Protein motifs (from Interpro)
Interpro ID Name
 IPR005485  Ribosomal protein L5 eukaryotic/L18 archaeal
 IPR025607  Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000027 ribosomal large subunit assembly IBA
 biological_processGO:0006412 translation IBA
 biological_processGO:0043009 chordate embryonic development IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit IBA
 molecular_functionGO:0003735 structural constituent of ribosome IBA
 molecular_functionGO:0008097 5S rRNA binding IBA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
SRP-dependent cotranslational protein targeting to membrane
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain morphology , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary morphology , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle morphology , abnormal
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 ZFA:0000114 heart heart nucleate erythrocyte decreased amount , abnormal
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 ZFA:0000445 optic tectum optic tectum morphology , abnormal
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 ZFA:0001094 whole organism whole organism increased amount , abnormal
whole organism decreased amount , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head apoptotic process increased occurrence , exacerbated
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 ZFA:0001117 post-vent region post-vent region morphology , abnormal
post-vent region curved ventral , abnormal
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 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton malformed , exacerbated
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 ZFA:0001580 neurocranium neurocranium malformed , exacerbated
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 ZFA:0009014 hematopoietic stem cell hematopoietic stem cell decreased amount , abnormal
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 ZFA:0009015 erythroid progenitor cell erythroid progenitor cell decreased amount , abnormal
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 ZFA:0009021 common myeloid progenitor common myeloid progenitor decreased amount , abnormal
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 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
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 ZFA:0009258 angioblastic mesenchymal cell angioblastic mesenchymal cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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