ENSDARG00000021257


Danio rerio

Features
Gene ID: ENSDARG00000021257
  
Biological name :eif3d
  
Synonyms : eif3d / eukaryotic translation initiation factor 3, subunit D / Q6TH15
  
Possible biological names infered from orthology : O15371 / O70194
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 29640837
Gene end: 29654925
  
Corresponding Affymetrix probe sets: Dr.20598.1.S1_at (Zebrafish Array)   NM_200016_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000116681
Ensembl peptide - ENSDARP00000126192
Ensembl peptide - ENSDARP00000126265
Ensembl peptide - ENSDARP00000011011
Ensembl peptide - ENSDARP00000126163
NCBI entrez gene - 336498     See in Manteia.
RefSeq - NM_200016
RefSeq Peptide - NP_956310
swissprot - I3ITC9
swissprot - I3ITA1
swissprot - I3ITJ7
swissprot - Q6TH15
swissprot - Z4YIM6
ZFIN ID - ZDB-GENE-030131-8442
Ensembl - ENSDARG00000021257
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EIF3DENSGALG00000012529Gallus gallus
 EIF3DENSG00000100353Homo sapiens
 Eif3dENSMUSG00000016554Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007783  Eukaryotic translation initiation factor 3 subunit D
 IPR011989  Armadillo-like helical


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001732 formation of cytoplasmic translation initiation complex IEA
 biological_processGO:0002183 cytoplasmic translational initiation IEA
 biological_processGO:0002191 cap-dependent translational initiation ISS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IBA
 cellular_componentGO:0016282 eukaryotic 43S preinitiation complex IEA
 cellular_componentGO:0033290 eukaryotic 48S preinitiation complex IEA
 molecular_functionGO:0003723 RNA binding ISS
 molecular_functionGO:0003743 translation initiation factor activity IBA
 molecular_functionGO:0098808 mRNA cap binding ISS


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk circular , abnormal
yolk grey , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
Show

 ZFA:0000114 heart heart quality , abnormal
Show

 ZFA:0000123 liver liver quality , abnormal
liver hypoplastic , abnormal
Show

 ZFA:0001094 whole organism whole organism viability , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr