ENSG00000100353


Homo sapiens

Features
Gene ID: ENSG00000100353
  
Biological name :EIF3D
  
Synonyms : EIF3D / eukaryotic translation initiation factor 3 subunit D / O15371
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q12.3
Gene start: 36510850
Gene end: 36529436
  
Corresponding Affymetrix probe sets: 200005_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000216190
Ensembl peptide - ENSP00000385212
Ensembl peptide - ENSP00000487325
Ensembl peptide - ENSP00000403584
Ensembl peptide - ENSP00000391061
Ensembl peptide - ENSP00000390438
Ensembl peptide - ENSP00000385812
NCBI entrez gene - 8664     See in Manteia.
OMIM - 603915
RefSeq - NM_003753
RefSeq Peptide - NP_003744
swissprot - B0QYA5
swissprot - B0QYA4
swissprot - A0A0D9SGB5
swissprot - B0QYA8
swissprot - O15371
swissprot - B0QYA6
Ensembl - ENSG00000100353
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif3dENSDARG00000021257Danio rerio
 EIF3DENSGALG00000012529Gallus gallus
 Eif3dENSMUSG00000016554Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007783  Eukaryotic translation initiation factor 3 subunit D
 IPR011989  Armadillo-like helical


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001732 formation of cytoplasmic translation initiation complex IEA
 biological_processGO:0002191 cap-dependent translational initiation IDA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0045727 positive regulation of translation IPI
 biological_processGO:0075522 IRES-dependent viral translational initiation IDA
 biological_processGO:0075525 viral translational termination-reinitiation IDA
 biological_processGO:1902416 positive regulation of mRNA binding IPI
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0098808 mRNA cap binding IDA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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