ENSDARG00000022372


Danio rerio

Features
Gene ID: ENSDARG00000022372
  
Biological name :kng1
  
Synonyms : kininogen 1 / kng1
  
Possible biological names infered from orthology : Kininogen-1 Kininogen-1 heavy chain Bradykinin Kininogen-1 light chain / kininogen 2 / Kng2 / O08677 / P01042
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 36839080
Gene end: 36876133
  
Corresponding Affymetrix probe sets: Dr.17618.1.A1_at (Zebrafish Array)   NM_001005981_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000036317
Ensembl peptide - ENSDARP00000121064
Ensembl peptide - ENSDARP00000119240
NCBI entrez gene - 449808     See in Manteia.
RefSeq - NM_001005981
RefSeq - XM_005170550
RefSeq Peptide - NP_001005981
swissprot - E9QFM6
swissprot - Q1LYJ7
swissprot - E9QEH2
ZFIN ID - ZDB-GENE-041010-56
Ensembl - ENSDARG00000022372
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KNG1ENSGALG00000046159Gallus gallus
 KNG1ENSG00000113889Homo sapiens
 Kng1ENSMUSG00000022875Mus musculus
 Kng2ENSMUSG00000060459Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000010  Cystatin domain
 IPR027358  Kininogen-type cystatin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IBA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0030195 negative regulation of blood coagulation IBA
 biological_processGO:1904888 cranial skeletal system development IMP
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0004869 cysteine-type endopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Intrinsic Pathway of Fibrin Clot Formation
Peptide ligand-binding receptors
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
G alpha (q) signalling events
G alpha (i) signalling events
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000547 mouth mouth atretic , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage distance ethmoid cartilage , abnormal
Meckels cartilage orientation whole organism anterior-posterior axis, abnormal
Meckels cartilage truncated , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage shape , abnormal
ceratohyal cartilage right angle to whole organism anterior-posterior axis, abnormal
Show

 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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