ENSDARG00000023287


Danio rerio

Features
Gene ID: ENSDARG00000023287
  
Biological name :hsd17b3
  
Synonyms : hsd17b3 / hydroxysteroid (17-beta) dehydrogenase 3
  
Possible biological names infered from orthology : P37058 / P70385
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 29852353
Gene end: 29876413
  
Corresponding Affymetrix probe sets: Dr.25769.1.S1_at (Zebrafish Array)   NM_200364_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000061980
Ensembl peptide - ENSDARP00000124637
NCBI entrez gene - 393335     See in Manteia.
RefSeq - NM_200364
RefSeq Peptide - NP_956658
swissprot - Q7T396
ZFIN ID - ZDB-GENE-040426-1339
Ensembl - ENSDARG00000023287
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HSD17B3ENSGALG00000045920Gallus gallus
 P37058ENSG00000130948Homo sapiens
 P70385ENSMUSG00000033122Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6P3L6 / hsd17b12a / hydroxysteroid (17-beta) dehydrogenase 12a / O70503* / Q53GQ0* / HSD17B12* / hydroxysteroid 17-beta dehydrogenase 12*ENSDARG0000001570942
hsd20b2 / hydroxysteroid (20-beta) dehydrogenase 2ENSDARG0000003133640
Q6QA33 / hsd17b12b / hydroxysteroid (17-beta) dehydrogenase 12b / O70503* / Q53GQ0* / HSD17B12* / hydroxysteroid 17-beta dehydrogenase 12*ENSDARG0000003587240
hsdl1 / A5WWC6 / hydroxysteroid dehydrogenase like 1 / Q3SXM5*ENSDARG0000004173625


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR016040  NAD(P)-binding domain
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR033281  Testosterone 17-beta-dehydrogenase 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006702 androgen biosynthetic process IDA
 biological_processGO:0030539 male genitalia development IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0061370 testosterone biosynthetic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity IDA


Pathways (from Reactome)
Pathway description
Androgen biosynthesis
Synthesis of very long-chain fatty acyl-CoAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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