ENSDARG00000015709


Danio rerio

Features
Gene ID: ENSDARG00000015709
  
Biological name :hsd17b12a
  
Synonyms : hsd17b12a / hydroxysteroid (17-beta) dehydrogenase 12a / Q6P3L6
  
Possible biological names infered from orthology : HSD17B12 / hydroxysteroid 17-beta dehydrogenase 12 / O70503 / Q53GQ0
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 30196039
Gene end: 30230559
  
Corresponding Affymetrix probe sets: Dr.9000.1.S1_at (Zebrafish Array)   NM_200881_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000014003
NCBI entrez gene - 327417     See in Manteia.
RefSeq - NM_200881
RefSeq Peptide - NP_957175
swissprot - Q6P3L6
ZFIN ID - ZDB-GENE-030131-5628
Ensembl - ENSDARG00000015709
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HSD17B12ENSGALG00000036787Gallus gallus
 Q53GQ0ENSG00000149084Homo sapiens
 O70503ENSMUSG00000027195Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6QA33 / hsd17b12b / hydroxysteroid (17-beta) dehydrogenase 12b / O70503* / Q53GQ0* / HSD17B12* / hydroxysteroid 17-beta dehydrogenase 12*ENSDARG0000003587266
hsd20b2 / hydroxysteroid (20-beta) dehydrogenase 2ENSDARG0000003133640
hsd17b3 / hydroxysteroid (17-beta) dehydrogenase 3 / P37058* / P70385*ENSDARG0000002328731
hsdl1 / A5WWC6 / hydroxysteroid dehydrogenase like 1 / Q3SXM5*ENSDARG0000004173628


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR016040  NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0006703 estrogen biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004303 estradiol 17-beta-dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0102339 3-oxo-arachidoyl-CoA reductase activity IEA
 molecular_functionGO:0102340 3-oxo-behenoyl-CoA reductase activity IEA
 molecular_functionGO:0102341 3-oxo-lignoceroyl-CoA reductase activity IEA
 molecular_functionGO:0102342 3-oxo-cerotoyl-CoA reductase activity IEA


Pathways (from Reactome)
Pathway description
Androgen biosynthesis
Synthesis of very long-chain fatty acyl-CoAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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