ENSDARG00000023722


Danio rerio

Features
Gene ID: ENSDARG00000023722
  
Biological name :hcrtr2
  
Synonyms : hcrtr2 / hypocretin (orexin) receptor 2
  
Possible biological names infered from orthology : hypocretin receptor 2 / O43614 / Orexin receptor type 2 / P58308
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 2020215
Gene end: 2060713
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000029101
NCBI entrez gene - 561260     See in Manteia.
RefSeq - NM_001079868
RefSeq Peptide - NP_001073337
swissprot - A1YQE3
ZFIN ID - ZDB-GENE-070228-3
Ensembl - ENSDARG00000023722
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HCRTR2ENSGALG00000016297Gallus gallus
 HCRTR2ENSG00000137252Homo sapiens
 Hcrtr2ENSMUSG00000032360Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NPFFR2 / neuropeptide FF receptor 2a / Q9Y5X5* / neuropeptide FF receptor 2*ENSDARG0000003363529
npffr1l2 / neuropeptide FF receptor 1 like 2ENSDARG0000006263128
npffr2b / neuropeptide FF receptor 2b / NPFFR2* / Q9Y5X5* / Q924H0* / neuropeptide FF receptor 2*ENSDARG0000006070228
npffr1l3 / neuropeptide FF receptor 1 like 3ENSDARG0000001071228
npffr1l1 / neuropeptide FF receptor 1 like 1ENSDARG0000005420327
si:dkey-1h24.2 / CCKBR* / P32239* / P56481* / cholecystokinin B receptor* / Gastrin/cholecystokinin type B receptor *ENSDARG0000007411723
CCKBR / cholecystokinin B receptor / P32239*ENSDARG0000007682423
galr1a / galanin receptor 1a / GALR1* / P47211* / P56479* / galanin receptor 1* / Galanin receptor type 1 *ENSDARG0000000552223
CCKAR / cholecystokinin A receptor / P32238*ENSDARG0000005208922
galr1b / galanin receptor 1bENSDARG0000007916521
galr2b / galanin receptor 2b / GALR3* / O60755* / O88853* / galanin receptor 3* / Galanin receptor type 3 *ENSDARG0000010511321
galr2a / galanin receptor 2a / GALR2* / O43603* / O88854* / galanin receptor 2* / Galanin receptor type 2 *ENSDARG0000002085321
kiss1rb / KISS1 receptor bENSDARG0000006756321
kiss1ra / KISS1 receptor a / KISS1R* / Q91V45* / Q969F8* / KISS1 receptor* / Mus musculus KISS1 receptor (Kiss1r), transcript variant 2, mRNA.*ENSDARG0000000272820
npffr1 / neuropeptide FF receptor 1 / Q9GZQ6*ENSDARG0000011199720
qrfpr4 / pyroglutamylated RFamide peptide receptor 4ENSDARG0000009265220
QRFPR / pyroglutamylated RFamide peptide receptor / Q96P65*ENSDARG0000010196919
qrfpra / pyroglutamylated RFamide peptide receptor a / QRFPR* / P83861* / Q96P65* / C130060K24Rik* / RIKEN cDNA C130060K24 gene* / pyroglutamylated RFamide peptide receptor*ENSDARG0000003934917


Protein motifs (from Interpro)
Interpro ID Name
 IPR000204  Orexin receptor family
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR004060  Orexin receptor 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007631 feeding behavior IBA
 biological_processGO:0022410 circadian sleep/wake cycle process IEA
 biological_processGO:0030186 melatonin metabolic process IMP
 biological_processGO:0032870 cellular response to hormone stimulus IBA
 biological_processGO:0045187 regulation of circadian sleep/wake cycle, sleep IMP
 biological_processGO:0048512 circadian behavior IMP
 biological_processGO:1901652 response to peptide IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0016499 orexin receptor activity IBA
 molecular_functionGO:0042277 peptide binding IBA


Pathways (from Reactome)
Pathway description
Orexin and neuropeptides FF and QRFP bind to their respective receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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