ENSDARG00000026629


Danio rerio

Features
Gene ID: ENSDARG00000026629
  
Biological name :gmds
  
Synonyms : GDP-mannose 4,6-dehydratase / gmds
  
Possible biological names infered from orthology : O60547 / Q8K0C9
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 26709009
Gene end: 26822550
  
Corresponding Affymetrix probe sets: Dr.2695.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000046763
Ensembl peptide - ENSDARP00000094011
Ensembl peptide - ENSDARP00000119997
Ensembl peptide - ENSDARP00000122672
NCBI entrez gene - 393461     See in Manteia.
RefSeq - NM_200489
RefSeq - NM_001102475
RefSeq Peptide - NP_956783
RefSeq Peptide - NP_001095945
swissprot - Q1LVF8
swissprot - Q7T155
swissprot - Q1LVF6
swissprot - F1QPT3
ZFIN ID - ZDB-GENE-050419-45
Ensembl - ENSDARG00000026629
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000029497Gallus gallus
 ENSGALG00000033170Gallus gallus
 GMDSENSG00000112699Homo sapiens
 GmdsENSMUSG00000038372Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006368  GDP-mannose 4,6-dehydratase
 IPR016040  NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007219 Notch signaling pathway IMP
 biological_processGO:0010842 retina layer formation IMP
 biological_processGO:0019673 GDP-mannose metabolic process IEA
 biological_processGO:0021564 vagus nerve development IMP
 biological_processGO:0021744 dorsal motor nucleus of vagus nerve development IMP
 biological_processGO:0036065 fucosylation IEA
 biological_processGO:0042351 "de novo" GDP-L-fucose biosynthetic process ISS
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0008417 fucosyltransferase activity IMP
 molecular_functionGO:0008446 GDP-mannose 4,6-dehydratase activity IEA
 molecular_functionGO:0070401 NADP+ binding ISS


Pathways (from Reactome)
Pathway description
GDP-fucose biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain morphology , abnormal
Show

 ZFA:0000075 spinal cord spinal cord glial cell decreased amount , abnormal
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 ZFA:0001094 whole organism whole organism dead , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved dorsal , abnormal
post-vent region curved , abnormal
Show

 ZFA:0001329 retinal inner plexiform layer retinal inner plexiform layer disorganized , abnormal
Show

 ZFA:0001330 retinal outer plexiform layer retinal outer plexiform layer disorganized , abnormal
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 ZFA:0001695 dorsolateral motor nucleus of vagal nerve dorsolateral motor nucleus of vagal nerve fused with dorsolateral motor nucleus of vagal nerve , abnormal
dorsolateral motor nucleus of vagal nerve mislocalised medially , abnormal
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 ZFA:0009149 Mauthner neuron Mauthner neuron increased amount , abnormal
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 ZFA:0009247 secondary motor neuron secondary motor neuron decreased amount , abnormal
secondary motor neuron axon morphology , abnormal
secondary motor neuron irregular spatial pattern , abnormal
secondary motor neuron axon decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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