ENSDARG00000032056


Danio rerio

Features
Gene ID: ENSDARG00000032056
  
Biological name :arl6
  
Synonyms : ADP-ribosylation factor-like 6 / arl6 / Q5M9P8
  
Possible biological names infered from orthology : ADP ribosylation factor like GTPase 6 / ADP-ribosylation factor-like protein 6 / O88848 / Q9H0F7
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 34203817
Gene end: 34233938
  
Corresponding Affymetrix probe sets: Dr.18638.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000147421
Ensembl peptide - ENSDARP00000155069
Ensembl peptide - ENSDARP00000046093
NCBI entrez gene - 494134     See in Manteia.
RefSeq - XM_021474253
RefSeq Peptide - NP_001008733
swissprot - B2GRI2
swissprot - Q5M9P8
ZFIN ID - ZDB-GENE-041219-2
Ensembl - ENSDARG00000032056
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARL6ENSGALG00000019215Gallus gallus
 ARL6ENSG00000113966Homo sapiens
 Arl6ENSMUSG00000022722Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arl1 / ADP-ribosylation factor-like 1 / P40616* / P61211* / ADP ribosylation factor like GTPase 1* / ADP-ribosylation factor-like protein 1 *ENSDARG0000010168037
arl8 / ADP-ribosylation factor-like 8 / ARL5B* / Q96KC2* / ADP ribosylation factor like GTPase 5B*ENSDARG0000009470937
arl5c / ADP-ribosylation factor-like 5C / Q6P068* / A6NH57* / ADP ribosylation factor like GTPase 5C* / ADP-ribosylation factor-like protein 5C *ENSDARG0000003571937
arl5a / ADP-ribosylation factor-like 5A / Q80ZU0* / Q9Y689* / ADP ribosylation factor like GTPase 5A* / ADP-ribosylation factor-like protein 5A *ENSDARG0000001862736


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0007369 gastrulation IMP
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0008593 regulation of Notch signaling pathway IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0032402 melanosome transport IMP
 biological_processGO:0033339 pectoral fin development IGI
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0060170 ciliary membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
BBSome-mediated cargo-targeting to cilium


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle decreased size , abnormal
Kupffers vesicle aplastic , abnormal
Show

 ZFA:0000135 notochord notochord kinked , abnormal
Show

 ZFA:0000155 somite somite increased width , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014477 sstr3 / somatostatin receptor 3 / P30935* / P32745* / Somatostatin receptor type 3 *  / complex / reaction
 ENSDARG00000103662 si:zfos-169g10.2 / SSTR3* / P32745* / P30935* / somatostatin receptor 3* / Somatostatin receptor type 3 *  / reaction / complex






 

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