ENSDARG00000032831


Danio rerio

Features
Gene ID: ENSDARG00000032831
  
Biological name :htra1a
  
Synonyms : htra1a / HtrA serine peptidase 1a / Q6GMI0
  
Possible biological names infered from orthology : HTRA1 / HtrA serine peptidase 1 / Q92743 / Q9R118 / Serine protease HTRA1
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 21919131
Gene end: 21959556
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000048135
NCBI entrez gene - 431766     See in Manteia.
RefSeq - NM_001002219
RefSeq Peptide - NP_001002219
swissprot - B2GT42
swissprot - Q6GMI0
ZFIN ID - ZDB-GENE-040704-64
Ensembl - ENSDARG00000032831
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HTRA1ENSGALG00000041140Gallus gallus
 HTRA1ENSG00000166033Homo sapiens
 Htra1ENSMUSG00000006205Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
htra1b / A9JRB3 / HtrA serine peptidase 1b / HTRA1* / Q9R118* / Q92743* / Serine protease HTRA1 * / HtrA serine peptidase 1*ENSDARG0000001490780
htra4 / HtrA serine peptidase 4 / A2RT60* / P83105* / Serine protease HTRA4 *ENSDARG0000000594358
htra3a / HtrA serine peptidase 3a / HTRA3* / P83110* / Q9D236* / Serine protease HTRA3 * / HtrA serine peptidase 3*ENSDARG0000005289551
HTRA3 / HtrA serine peptidase 3 / P83110*ENSDARG0000001092547
si:dkey-33c12.12 / si:dkey-112g5.12 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000006990941
zgc:174193 / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000008874334
si:dkey-265c15.6 / si:dkey-112g5.12 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000007671332
si:dkey-112g5.16 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009220224
zgc:173425 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009474123
si:dkey-33c12.11 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009300523
si:dkey-19p15.4 / si:dkey-112g5.14 / HTRA2 (1 of many) / HTRA2* / Q9JIY5* / O43464* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009531423
CR848040.4 / HTRA2* / Q9JIY5* / O43464* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000011510623
si:dkey-33c12.12 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009554523
si:dkey-112g5.13 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009206123
si:dkey-84o3.7 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009213323
si:dkey-33c12.14 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009238023
si:dkey-84o3.7 / si:dkey-84o3.3 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000007013823
si:dkey-19p15.4 / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000011163323
si:dkey-84o3.7 / si:dkey-84o3.3 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009568723
si:dkey-112g5.12 / si:dkey-112g5.11 / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009209423


Protein motifs (from Interpro)
Interpro ID Name
 IPR000867  Insulin-like growth factor-binding protein, IGFBP
 IPR001478  PDZ domain
 IPR001940  Peptidase S1C
 IPR002350  Kazal domain
 IPR009003  Peptidase S1, PA clan
 IPR009030  Growth factor receptor cysteine-rich domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0040036 regulation of fibroblast growth factor receptor signaling pathway IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005520 insulin-like growth factor binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019838 growth factor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000155 somite somite increased size , abnormal
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 ZFA:0001058 caudal fin caudal fin kinked , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism wholly dorsalized , abnormal
whole organism elongated , abnormal
Show

 ZFA:0001605 caudal fin lower lobe caudal fin lower lobe absent , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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