ENSDARG00000032976


Danio rerio

Features
Gene ID: ENSDARG00000032976
  
Biological name :cmlc1
  
Synonyms : cardiac myosin light chain-1 / cmlc1
  
Possible biological names infered from orthology : Mus musculus myosin, light polypeptide 4 (Myl4), transcript variant 2, mRNA. / MYL4 / myosin light chain 4 / P12829
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 64167620
Gene end: 64168415
  
Corresponding Affymetrix probe sets: Dr.8379.1.S1_at (Zebrafish Array)   NM_131692_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000048394
NCBI entrez gene - 64671     See in Manteia.
RefSeq - NM_131692
RefSeq Peptide - NP_571767
swissprot - B0R0F7
ZFIN ID - ZDB-GENE-030522-1
Ensembl - ENSDARG00000032976
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYL4ENSGALG00000000585Gallus gallus
 MYL4ENSG00000198336Homo sapiens
 Myl4ENSMUSG00000061086Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
myl4 / myosin, light chain 4, alkali; atrial, embryonic / P12829* / myosin light chain 4* / Mus musculus myosin, light polypeptide 4 (Myl4), transcript variant 2, mRNA.*ENSDARG0000001151973
myl13 / myosin, light chain 13ENSDARG0000004224569
zgc:163073 / MYL3* / P08590* / P09542* / myosin light chain 3*ENSDARG0000009971263
myl1 / myosin, light chain 1, alkali; skeletal, fast / P05977* / P05976* / myosin light chain 1* / Myosin light chain 1/3, skeletal muscle isoform *ENSDARG0000001419657
zgc:153867 / MYL6* / MYL6B* / P60660* / P14649* / Q60605* / Q8CI43* / myosin light chain 6* / myosin light chain 6B* / myosin, light polypeptide 6, alkali, smooth muscle and non-muscle*ENSDARG0000003373856
myl6 / myosin, light chain 6, alkali, smooth muscle and non-muscle / MYL6B* / Q8CI43* / P14649* / P60660* / Q60605* / myosin light chain 6* / myosin light chain 6B* / myosin, light polypept...ENSDARG0000000849455
mylz3 / myosin, light polypeptide 3, skeletal muscle / MYL1* / P05977* / P05976* / myosin light chain 1* / Myosin light chain 1/3, skeletal muscle isoform *ENSDARG0000001744146


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0045214 sarcomere organization IMP
 biological_processGO:0048738 cardiac muscle tissue development IMP
 biological_processGO:0055005 ventricular cardiac myofibril assembly IMP
 biological_processGO:0055015 ventricular cardiac muscle cell development IMP
 biological_processGO:0060047 heart contraction IMP
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle striated muscle myosin thick filament absent , abnormal
cardiac ventricle sarcomere immature , abnormal
cardiac ventricle contractility , abnormal
cardiac ventricle decreased diameter , abnormal
cardiac ventricle collapsed , abnormal
cardiac ventricle increased volume , abnormal
cardiac ventricle increased size , abnormal
cardiac ventricle decreased contractility , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000114 heart heart decreased strength , abnormal
heart quality , abnormal
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 ZFA:0000471 atrium atrium contractility , abnormal
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 ZFA:0001094 whole organism whole organism decreased life span , abnormal
Show

 ZFA:0001315 atrioventricular canal atrioventricular canal decreased amount , abnormal
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 ZFA:0001439 anatomical system anatomical system quality , abnormal
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 ZFA:0009316 cardiac muscle cell cardiac muscle cell sarcomere increased length , abnormal
cardiac muscle cell shape , abnormal
cardiac muscle cell increased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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