ENSDARG00000034534


Danio rerio

Features
Gene ID: ENSDARG00000034534
  
Biological name :atp6v1aa
  
Synonyms : atp6v1aa / ATPase H+ transporting V1 subunit Aa
  
Possible biological names infered from orthology : ATP6V1A / ATPase H+ transporting V1 subunit A / Mus musculus ATPase, H+ transporting, lysosomal V1 subunit A (Atp6v1a), transcript variant 2, mRNA. / P38606 / P50516
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 24245682
Gene end: 24259992
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000049002
NCBI entrez gene - 394110     See in Manteia.
RefSeq - NM_201135
RefSeq Peptide - NP_957429
swissprot - A2BEN1
ZFIN ID - ZDB-GENE-040426-1143
Ensembl - ENSDARG00000034534
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP6V1AENSGALG00000014800Gallus gallus
 P38606ENSG00000114573Homo sapiens
 P50516ENSMUSG00000052459Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
atp6v1ab / ATPase H+ transporting V1 subunit Ab / P50516* / P38606* / ATP6V1A* / ATPase H+ transporting V1 subunit A* / Mus musculus ATPase, H+ transporting, lysosomal V1 subunit A (Atp6v1a...ENSDARG0000007631897


Protein motifs (from Interpro)
Interpro ID Name
 IPR000194  ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain
 IPR004100  ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain
 IPR005725  ATPase, V1 complex, subunit A
 IPR020003  ATPase, alpha/beta subunit, nucleotide-binding domain, active site
 IPR022878  V-type ATP synthase catalytic alpha chain
 IPR024034  ATPase, F1/V1 complex, beta/alpha subunit, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031686  ATPsynthase alpha/beta subunit, N-terminal extension


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006874 cellular calcium ion homeostasis IMP
 biological_processGO:0006883 cellular sodium ion homeostasis IMP
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 biological_processGO:0046034 ATP metabolic process IEA
 cellular_componentGO:0005765 lysosomal membrane IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0033180 proton-transporting V-type ATPase, V1 domain IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015078 proton transmembrane transporter activity IMP
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism IBA


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

 ZFA:0001117 post-vent region post-vent region deformed , abnormal
Show

 ZFA:0005169 intrahepatic bile duct intrahepatic bile duct distended , abnormal
intrahepatic bile duct decreased amount , abnormal
Show

 ZFA:0005327 vH ionocyte vH ionocyte flux , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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