ENSDARG00000035634


Danio rerio

Features
Gene ID: ENSDARG00000035634
  
Biological name :rfc5
  
Synonyms : replication factor C (activator 1) 5 / rfc5
  
Possible biological names infered from orthology : P40937 / Q9D0F6 / replication factor C subunit 5
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 12528693
Gene end: 12549732
  
Corresponding Affymetrix probe sets: Dr.4387.3.S1_at (Zebrafish Array)   NM_001003862_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000051669
NCBI entrez gene - 445385     See in Manteia.
RefSeq - NM_001003862
RefSeq Peptide - NP_001003862
swissprot - Q6DRK4
ZFIN ID - ZDB-GENE-040907-1
Ensembl - ENSDARG00000035634
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RFC5ENSGALG00000026517Gallus gallus
 RFC5ENSG00000111445Homo sapiens
 Rfc5ENSMUSG00000029363Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR008921  DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
 IPR013748  Replication factor C, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006261 DNA-dependent DNA replication IBA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0060041 retina development in camera-type eye IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005663 DNA replication factor C complex IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003689 DNA clamp loader activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Polymerase switching on the C-strand of the telomere
Activation of ATR in response to replication stress
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Processing of DNA double-strand break ends
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Regulation of TP53 Activity through Phosphorylation
Polymerase switching
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000076 swim bladder swim bladder quality , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000152 retina retina quality , abnormal
Show

 ZFA:0001114 head head decreased width , abnormal
head pointed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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