ENSDARG00000037109


Danio rerio

Features
Gene ID: ENSDARG00000037109
  
Biological name :pwp2h
  
Synonyms : pwp2h / PWP2 periodic tryptophan protein homolog (yeast)
  
Possible biological names infered from orthology : FP565260.1 / PWP2 / PWP2, small subunit processome component / Q15269 / Q8BU03
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 28898945
Gene end: 28950366
  
Corresponding Affymetrix probe sets: Dr.3590.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000101591
swissprot - F1RAC4
ZFIN ID - ZDB-GENE-021031-3
Ensembl - ENSDARG00000037109
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000045726Gallus gallus
 FP565260.1ENSG00000275464Homo sapiens
 PWP2ENSG00000241945Homo sapiens
 Pwp2ENSMUSG00000032834Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR007148  Small-subunit processome, Utp12
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR027145  Periodic tryptophan protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000028 ribosomal small subunit assembly IMP
 biological_processGO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0042254 ribosome biogenesis IMP
 biological_processGO:0055123 digestive system development IMP
 cellular_componentGO:0032040 small-subunit processome IBA
 cellular_componentGO:0034388 Pwp2p-containing subcomplex of 90S preribosome IBA
 molecular_functionGO:0030515 snoRNA binding IBA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000076 swim bladder swim bladder uninflated , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000123 liver liver decreased size , abnormal
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 ZFA:0000140 pancreas pancreas decreased size , abnormal
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 ZFA:0001076 intestinal bulb intestinal bulb decreased size , abnormal
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 ZFA:0001094 whole organism whole organism dead , abnormal
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 ZFA:0001114 head head malformed , abnormal
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 ZFA:0001338 intestine intestine epithelial cell cuboid , abnormal
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 ZFA:0005124 intestinal epithelium intestinal epithelium shape , abnormal
intestinal epithelium decreased thickness , abnormal
intestinal epithelium decreased size , abnormal
intestinal epithelium autophagosome increased amount , abnormal
intestinal epithelium autolysosome increased amount , abnormal
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 ZFA:0005125 intestinal villus intestinal villus sparse , abnormal
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 ZFA:0005126 intestinal bulb epithelium intestinal bulb epithelium apical-basal axis relative to substrate decreased length , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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