ENSDARG00000037153


Danio rerio

Features
Gene ID: ENSDARG00000037153
  
Biological name :atp6ap1b
  
Synonyms : atp6ap1b / ATPase H+ transporting accessory protein 1b
  
Possible biological names infered from orthology : ATP6AP1 / ATPase H+ transporting accessory protein 1 / ATPase, H+ transporting, lysosomal accessory protein 1 / Q15904 / Q9R1Q9
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 26079467
Gene end: 26094178
  
Corresponding Affymetrix probe sets: Dr.4628.1.S1_at (Zebrafish Array)   NM_173265_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000110078
NCBI entrez gene - 195824     See in Manteia.
RefSeq - NM_173265
RefSeq Peptide - NP_775372
swissprot - A2AR67
ZFIN ID - ZDB-GENE-020423-2
Ensembl - ENSDARG00000037153
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP6AP1ENSGALG00000008836Gallus gallus
 Q15904ENSG00000071553Homo sapiens
 Q9R1Q9ENSMUSG00000019087Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
atp6ap1a / ATPase H+ transporting accessory protein 1a / Q9R1Q9* / Q15904* / ATP6AP1* / ATPase H+ transporting accessory protein 1* / ATPase, H+ transporting, lysosomal accessory protein 1*ENSDARG0000004141747
atp6ap1la / ATPase H+ transporting accessory protein 1 like a / Q52LC2* / ATP6AP1L* / ATPase H+ transporting accessory protein 1 like* / ATPase, H+ transporting, lysosomal accessory protein 1-like*ENSDARG0000009150920
atp6ap1lb / ATPase H+ transporting accessory protein 1 like b / Q52LC2* / ATP6AP1L* / ATPase H+ transporting accessory protein 1 like* / ATPase, H+ transporting, lysosomal accessory protein 1-like*ENSDARG0000009096318


Protein motifs (from Interpro)
Interpro ID Name
 IPR008388  ATPase, V1 complex, subunit S1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003140 determination of left/right asymmetry in lateral mesoderm IMP
 biological_processGO:0003406 retinal pigment epithelium development IMP
 biological_processGO:0008057 eye pigment granule organization IMP
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 biological_processGO:0030641 regulation of cellular pH IMP
 biological_processGO:0032438 melanosome organization IMP
 biological_processGO:0034613 cellular protein localization IMP
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0060041 retina development in camera-type eye IMP
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 biological_processGO:0072659 protein localization to plasma membrane IMP
 biological_processGO:1901207 regulation of heart looping IMP
 biological_processGO:1902017 regulation of cilium assembly IMP
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0033180 proton-transporting V-type ATPase, V1 domain IEA
 molecular_functionGO:0046933 proton-transporting ATP synthase activity, rotational mechanism IEA
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism IEA


Pathways (from Reactome)
Pathway description
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cell decreased amount , abnormal
Kupffers vesicle decreased size , abnormal
Kupffers vesicle cilium decreased length , abnormal
Kupffers vesicle cilium decreased amount , abnormal
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 ZFA:0000023 forerunner cell group forerunner cell group cytoplasm decreased acidity , abnormal
forerunner cell group decreased amount , abnormal
forerunner cell group plasma membrane decreased amount , abnormal
forerunner cell group cell proliferation decreased occurrence , abnormal
forerunner cell group cell decreased amount , abnormal
Show

 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
Show

 ZFA:0000041 mesoderm mesoderm mislocalised , abnormal
mesoderm right side mislocalised , abnormal
Show

 ZFA:0000086 EVL EVL plasma membrane decreased amount , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000112 gut gut hypoplastic , abnormal
gut quality , abnormal
Show

 ZFA:0000123 liver liver hypoplastic , abnormal
liver quality , abnormal
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 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium increased thickness , abnormal
retinal pigmented epithelium malformed , abnormal
retinal pigmented epithelium vacuolated , abnormal
retinal pigmented epithelium physical object quality , abnormal
retinal pigmented epithelium melanosome malformed , abnormal
retinal pigmented epithelium melanosome broken , abnormal
retinal pigmented epithelium melanosome decreased size , abnormal
retinal pigmented epithelium translucent , abnormal
retinal pigmented epithelium mottled , abnormal
retinal pigmented epithelium quality , abnormal
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 ZFA:0000152 retina retina malformed , abnormal
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 ZFA:0000243 neuromast neuromast kinocilium decreased length , abnormal
neuromast decreased size , abnormal
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 ZFA:0001094 whole organism whole organism decreased pigmentation , abnormal
whole organism viability , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head decreased pigmentation , abnormal
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 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer disorganized , abnormal
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 ZFA:0005169 intrahepatic bile duct intrahepatic bile duct distended , abnormal
intrahepatic bile duct decreased amount , abnormal
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 ZFA:0005220 larval melanophore stripe larval melanophore stripe melanocyte translucent , abnormal
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 ZFA:0009000 cell cell plasma membrane decreased amount , abnormal
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 ZFA:0009032 ciliated cell ciliated cell cell decreased amount , abnormal
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 ZFA:0009090 pigment cell pigment cell quality , abnormal
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 ZFA:0009091 melanocyte melanocyte increased size , abnormal
melanocyte malformed , abnormal
melanocyte translucent , abnormal
melanocyte degenerate , abnormal
melanocyte decreased pigmentation , abnormal
melanocyte degree of pigmentation , abnormal
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 ZFA:0009154 eye photoreceptor cell eye photoreceptor cell malformed , abnormal
eye photoreceptor cell photoreceptor outer segment malformed , abnormal
eye photoreceptor cell photoreceptor outer segment elongated , abnormal
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 ZFA:0009358 ciliated olfactory receptor neuron ciliated olfactory receptor neuron olfactory bulb development decreased occurrence , abnormal
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 ZFA:0009367 neuromast hair cell neuromast hair cell basal region decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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