ENSDARG00000037654


Danio rerio

Features
Gene ID: ENSDARG00000037654
  
Biological name :pmm2
  
Synonyms : phosphomannomutase 2 / pmm2
  
Possible biological names infered from orthology : O15305 / Q9Z2M7
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 9860381
Gene end: 9866856
  
Corresponding Affymetrix probe sets: Dr.13747.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000054847
NCBI entrez gene - 368229     See in Manteia.
swissprot - Q7ZTZ3
ZFIN ID - ZDB-GENE-030722-6
Ensembl - ENSDARG00000037654
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PMM2ENSGALG00000007326Gallus gallus
 PMM2ENSG00000140650Homo sapiens
 Pmm2ENSMUSG00000022711Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FQ311927.1 / PMM1* / Q92871* / phosphomannomutase 1*ENSDARG0000003839846
CABZ01117706.1 / PMM1* / Q92871* / phosphomannomutase 1*ENSDARG0000011587015


Protein motifs (from Interpro)
Interpro ID Name
 IPR005002  Phosphomannomutase
 IPR006379  HAD-superfamily hydrolase, subfamily IIB
 IPR023214  HAD superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006013 mannose metabolic process IBA
 biological_processGO:0006487 protein N-linked glycosylation IMP
 biological_processGO:0009298 GDP-mannose biosynthetic process IEA
 biological_processGO:0022008 neurogenesis IMP
 biological_processGO:0045047 protein targeting to ER IBA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IMP
 biological_processGO:0090171 chondrocyte morphogenesis IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004615 phosphomannomutase activity IBA
 molecular_functionGO:0016853 isomerase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of GDP-mannose


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord secondary motor neuron increased amount , abnormal
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 ZFA:0001094 whole organism whole organism circling , abnormal
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 ZFA:0001161 pectoral fin pectoral fin kinked , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage morphology , abnormal
Meckels cartilage decreased distance ceratohyal cartilage , abnormal
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 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage shape , abnormal
palatoquadrate cartilage decreased length , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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