ENSDARG00000038024


Danio rerio

Features
Gene ID: ENSDARG00000038024
  
Biological name :flr
  
Synonyms : A7YE96 / fleer / flr
  
Possible biological names infered from orthology : A2AKQ8 / Q86WT1 / Q8N4P2 / Q99J38 / Q9CY00 / tetratricopeptide repeat domain 30A / tetratricopeptide repeat domain 30A1 / tetratricopeptide repeat domain 30A2 / tetratricopeptide repeat domain 30B / TTC30A / Ttc30a1 / Ttc30a2 / TTC30B
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 28831450
Gene end: 28853935
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000101646
Ensembl peptide - ENSDARP00000157401
Ensembl peptide - ENSDARP00000147522
Ensembl peptide - ENSDARP00000055421
NCBI entrez gene - 797829     See in Manteia.
RefSeq - NM_001104649
RefSeq Peptide - NP_001098119
swissprot - A7YE96
swissprot - A0A0R4I9F6
ZFIN ID - ZDB-GENE-070117-2066
Ensembl - ENSDARG00000038024
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TTC30BENSGALG00000009224Gallus gallus
 Q86WT1ENSG00000197557Homo sapiens
 Q8N4P2ENSG00000196659Homo sapiens
 A2AKQ8ENSMUSG00000075272Mus musculus
 Q99J38ENSMUSG00000075271Mus musculus
 Q9CY00ENSMUSG00000075273Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR013105  Tetratricopeptide repeat 2
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001736 establishment of planar polarity IGI
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0018095 protein polyglutamylation IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0036372 opsin transport IGI
 biological_processGO:0042073 intraciliary transport IMP
 biological_processGO:0060271 cilium assembly IMP
 cellular_componentGO:0005879 axonemal microtubule IDA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0030992 intraciliary transport particle B IBA
 cellular_componentGO:0031514 motile cilium IDA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005215 transporter activity IMP
 molecular_functionGO:0070738 tubulin-glycine ligase activity IMP


Pathways (from Reactome)
Pathway description
Intraflagellar transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium decreased length , abnormal
Kupffers vesicle cilium decreased amount , abnormal
Show

 ZFA:0000008 brain brain hydrocephalic , abnormal
Show

 ZFA:0000047 peripheral olfactory organ peripheral olfactory organ cilium absent , abnormal
Show

 ZFA:0000048 olfactory placode olfactory placode cilium absent , abnormal
Show

 ZFA:0000075 spinal cord spinal cord cilium decreased length , abnormal
Show

 ZFA:0000107 eye eye quality , abnormal
eye degenerate , abnormal
Show

 ZFA:0000130 olfactory pit olfactory pit cilium decreased length , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct cilium decreased length , abnormal
pronephric duct cystic , abnormal
pronephric duct microtubule disorganized , abnormal
Show

 ZFA:0000151 pronephros pronephros cystic , abnormal
pronephros cilium decreased length , abnormal
pronephros multi-ciliated epithelial cell lacks parts or has fewer parts of type multi-ciliated epithelial cell cilium, abnormal
pronephros axoneme structure , abnormal
pronephros quality , abnormal
Show

 ZFA:0000243 neuromast neuromast cilium absent , abnormal
Show

 ZFA:0000282 sensory system sensory system quality , abnormal
Show

 ZFA:0000386 macula macula cilium absent , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis curved , abnormal
whole organism anterior-posterior axis curved ventral , abnormal
whole organism shape , abnormal
whole organism curved ventral , abnormal
Show

 ZFA:0001288 renal glomerulus renal glomerulus increased size , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0001558 pronephric tubule pronephric tubule epithelium flattened , abnormal
Show

 ZFA:0005284 glomerular capillary glomerular capillary distended , abnormal
Show

 ZFA:0009127 photoreceptor cell photoreceptor cell photoreceptor outer segment displaced to photoreceptor cell lateral surface, abnormal
photoreceptor cell absent , abnormal
photoreceptor cell ciliary basal body mislocalised , abnormal
photoreceptor cell degenerate , abnormal
Show

 ZFA:0009262 retinal cone cell retinal cone cell decreased amount , abnormal
retinal cone cell absence due to degeneration , abnormal
Show

 ZFA:0009275 retinal rod cell retinal rod cell malformed , abnormal
retinal rod cell decreased amount , abnormal
retinal rod cell absence due to degeneration , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell disoriented , abnormal
neuromast hair cell kinocilium decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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