ENSDARG00000041621


Danio rerio

Features
Gene ID: ENSDARG00000041621
  
Biological name :bbs2
  
Synonyms : Bardet-Biedl syndrome 2 / bbs2 / Q98SP7
  
Possible biological names infered from orthology : Bardet-Biedl syndrome 2 protein homolog / Q9BXC9 / Q9CWF6
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 17516569
Gene end: 17531483
  
Corresponding Affymetrix probe sets: Dr.1599.1.S1_at (Zebrafish Array)   NM_152887_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000060999
Ensembl peptide - ENSDARP00000152776
NCBI entrez gene - 259187     See in Manteia.
RefSeq - NM_152887
RefSeq Peptide - NP_690843
swissprot - Q98SP7
ZFIN ID - ZDB-GENE-020801-1
Ensembl - ENSDARG00000041621
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BBS2ENSGALG00000042415Gallus gallus
 BBS2ENSG00000125124Homo sapiens
 Bbs2ENSMUSG00000031755Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016616  Bardet-Biedl syndrome 2 protein
 IPR017986  WD40-repeat-containing domain
 IPR029333  Ciliary BBSome complex subunit 2, C-terminal domain
 IPR029429  Ciliary BBSome complex subunit 2, middle region
 IPR029430  Ciliary BBSome complex subunit 2, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007368 determination of left/right symmetry IGI
 biological_processGO:0007369 gastrulation IMP
 biological_processGO:0032402 melanosome transport TAS
 biological_processGO:0046907 intracellular transport IMP
 biological_processGO:0051877 pigment granule aggregation in cell center IMP
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 biological_processGO:1903441 protein localization to ciliary membrane IBA
 biological_processGO:1905515 non-motile cilium assembly IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0031514 motile cilium IBA
 cellular_componentGO:0034464 BBSome IBA
 cellular_componentGO:0036064 ciliary basal body IBA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0060170 ciliary membrane IEA


Pathways (from Reactome)
Pathway description
BBSome-mediated cargo-targeting to cilium


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000135 notochord notochord increased width , abnormal
notochord kinked , abnormal
Show

 ZFA:0000155 somite somite increased width , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
Show

 ZFA:0001620 pronephric proximal convoluted tubule pronephric proximal convoluted tubule morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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