ENSDARG00000042793


Danio rerio

Features
Gene ID: ENSDARG00000042793
  
Biological name :tpp1
  
Synonyms : tpp1 / tripeptidyl peptidase I
  
Possible biological names infered from orthology : O14773 / O89023 / tripeptidyl peptidase 1
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 30843881
Gene end: 30855792
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000123755
Ensembl peptide - ENSDARP00000124672
swissprot - F8W2M8
swissprot - F8W584
ZFIN ID - ZDB-GENE-030131-6654
Ensembl - ENSDARG00000042793
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000029731Gallus gallus
 ENSGALG00000035308Gallus gallus
 TPP1ENSG00000166340Homo sapiens
 Tpp1ENSMUSG00000030894Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000209  Peptidase S8/S53 domain
 IPR015366  Peptidase S53, activation domain
 IPR030400  Sedolisin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007417 central nervous system development IMP
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0022008 neurogenesis IMP
 molecular_functionGO:0004175 endopeptidase activity IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0008240 tripeptidyl-peptidase activity ISS
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
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 ZFA:0000012 central nervous system central nervous system apoptotic , abnormal
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 ZFA:0000029 hindbrain hindbrain lysosome increased size , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000076 swim bladder swim bladder absent , abnormal
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 ZFA:0000100 cerebellum cerebellum absent , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
eye apoptotic , abnormal
Show

 ZFA:0000109 forebrain forebrain lysosome increased size , abnormal
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 ZFA:0000152 retina retina absent , abnormal
retina lysosome increased size , abnormal
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 ZFA:0000320 caudal commissure caudal commissure axon deformed , abnormal
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 ZFA:0000435 cranial nerve II cranial nerve II axon deformed , abnormal
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 ZFA:0000445 optic tectum optic tectum absent , abnormal
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 ZFA:0000600 cranial nerve IV cranial nerve IV axon deformed , abnormal
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 ZFA:0001094 whole organism whole organism degenerate , abnormal
whole organism dead , abnormal
Show

 ZFA:0001114 head head hypotrophic , abnormal
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 ZFA:0001115 trunk trunk curved , abnormal
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 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton absent , abnormal
mandibular arch skeleton decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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