ENSDARG00000044484


Danio rerio

Features
Gene ID: ENSDARG00000044484
  
Biological name :cdc23
  
Synonyms : cdc23 / CDC23 (cell division cycle 23, yeast, homolog)
  
Possible biological names infered from orthology : cell division cycle 23 / Q9UJX2
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 34849406
Gene end: 34880924
  
Corresponding Affymetrix probe sets: Dr.12680.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000065324
NCBI entrez gene - 393907     See in Manteia.
swissprot - Q7ZVH3
ZFIN ID - ZDB-GENE-040426-866
Ensembl - ENSDARG00000044484
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDC23ENSGALG00000007610Gallus gallus
 CDC23ENSG00000094880Homo sapiens
 Cdc23ENSMUSG00000024370Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007192  Cdc23
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030071 regulation of mitotic metaphase/anaphase transition IEA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005680 anaphase-promoting complex IEA


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr