ENSMUSG00000024370


Mus musculus

Features
Gene ID: ENSMUSG00000024370
  
Biological name :Cdc23
  
Synonyms : Cdc23 / cell division cycle 23
  
Possible biological names infered from orthology : Q9UJX2
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: B1
Gene start: 34630951
Gene end: 34651735
  
Corresponding Affymetrix probe sets: 10458164 (MoGene1.0st)   1433430_s_at (Mouse Genome 430 2.0 Array)   1443087_at (Mouse Genome 430 2.0 Array)   1460549_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025228
Ensembl peptide - ENSMUSP00000122420
NCBI entrez gene - 52563     See in Manteia.
MGI - MGI:1098815
RefSeq - XM_006526084
RefSeq - NM_178347
RefSeq Peptide - NP_848124
swissprot - A0A0R4J1W7
swissprot - G3X8W7
Ensembl - ENSMUSG00000024370
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc23ENSDARG00000044484Danio rerio
 CDC23ENSGALG00000007610Gallus gallus
 CDC23ENSG00000094880Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007192  Cdc23
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0007080 mitotic metaphase plate congression IEA
 biological_processGO:0030071 regulation of mitotic metaphase/anaphase transition IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070979 protein K11-linked ubiquitination IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005680 anaphase-promoting complex IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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