ENSDARG00000044588


Danio rerio

Features
Gene ID: ENSDARG00000044588
  
Biological name :emp2
  
Synonyms : emp2 / epithelial membrane protein 2 / F1QIK8
  
Possible biological names infered from orthology : O88662 / P54851
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 27027781
Gene end: 27056180
  
Corresponding Affymetrix probe sets: Dr.10980.1.S1_at (Zebrafish Array)   Dr.1300.1.A1_at (Zebrafish Array)   NM_001004119_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000065494
NCBI entrez gene - 445506     See in Manteia.
RefSeq - NM_001004119
RefSeq - XM_021470381
RefSeq Peptide - NP_001004119
swissprot - F1QIK8
ZFIN ID - ZDB-GENE-040822-24
Ensembl - ENSDARG00000044588
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EMP2ENSGALG00000027058Gallus gallus
 EMP2ENSG00000213853Homo sapiens
 Emp2ENSMUSG00000022505Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pmp22a / peripheral myelin protein 22a / PMP22* / Q01453* / peripheral myelin protein 22* / peripheral myelin protein 22 isoform 2 *ENSDARG0000010522350
emp1 / epithelial membrane protein 1 / P47801* / P54849*ENSDARG0000006963241
pmp22b / peripheral myelin protein 22b / PMP22* / Q01453* / peripheral myelin protein 22* / peripheral myelin protein 22 isoform 2 *ENSDARG0000006045739
si:dkey-264d12.4 / EMP3* / O35912* / P54852* / epithelial membrane protein 3*ENSDARG0000003642835
emp3b / epithelial membrane protein 3b / EMP3* / P54852* / O35912* / epithelial membrane protein 3*ENSDARG0000010146134


Protein motifs (from Interpro)
Interpro ID Name
 IPR003933  Epithelial membrane protein 2
 IPR004031  PMP-22/EMP/MP20/Claudin superfamily
 IPR004032  PMP-22/EMP/MP20


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003093 regulation of glomerular filtration IMP
 biological_processGO:0008284 positive regulation of cell proliferation ISS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk edematous , abnormal
Show

 ZFA:0001094 whole organism whole organism increased amount , abnormal
whole organism amount , ameliorated
Show

 ZFA:0001288 renal glomerulus renal glomerulus increased amount , abnormal
Show

 ZFA:0001557 pronephric glomerulus pronephric glomerulus lacks parts or has fewer parts of type pronephric podocyte podocyte foot, abnormal
Show

 ZFA:0001673 pronephric podocyte pronephric podocyte apoptotic , abnormal
Show

 ZFA:0005558 orbit orbit edematous , abnormal
orbit edematous , ameliorated
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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