ENSDARG00000045542


Danio rerio

Features
Gene ID: ENSDARG00000045542
  
Biological name :lamtor4
  
Synonyms : lamtor4 / late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 / Q0P3X8
  
Possible biological names infered from orthology : Q0VGL1 / Q8CF66 / Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR4, N-terminally processed
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 20051478
Gene end: 20054583
  
Corresponding Affymetrix probe sets: Dr.7372.1.S1_at (Zebrafish Array)   NM_001044950_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000115287
NCBI entrez gene - 561019     See in Manteia.
RefSeq - NM_001044950
RefSeq Peptide - NP_001038415
swissprot - Q0P3X8
ZFIN ID - ZDB-GENE-030131-7438
Ensembl - ENSDARG00000045542
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q0VGL1ENSG00000188186Homo sapiens
 Q8CF66ENSMUSG00000050552Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR034601  Ragulator complex protein LAMTOR4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008361 regulation of cell size ISS
 biological_processGO:0032008 positive regulation of TOR signaling ISS
 biological_processGO:0061462 protein localization to lysosome ISS
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071230 cellular response to amino acid stimulus ISS
 cellular_componentGO:0005764 lysosome ISS
 cellular_componentGO:0071986 Ragulator complex ISS
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity ISS
 molecular_functionGO:0032947 protein-containing complex scaffold activity ISS


Pathways (from Reactome)
Pathway description
Macroautophagy
mTOR signalling
mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain has fewer parts of type microglial cell , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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