ENSG00000188186


Homo sapiens

Features
Gene ID: ENSG00000188186
  
Biological name :LAMTOR4
  
Synonyms : LAMTOR4 / late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 / Q0VGL1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q22.1
Gene start: 100148907
Gene end: 100155944
  
Corresponding Affymetrix probe sets: 224890_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387926
Ensembl peptide - ENSP00000481202
Ensembl peptide - ENSP00000480432
Ensembl peptide - ENSP00000479685
Ensembl peptide - ENSP00000479500
Ensembl peptide - ENSP00000479176
Ensembl peptide - ENSP00000478095
Ensembl peptide - ENSP00000477680
Ensembl peptide - ENSP00000343118
NCBI entrez gene - 389541     See in Manteia.
RefSeq - XM_017012199
RefSeq - NM_001008395
RefSeq - NM_001318236
RefSeq - NM_001318237
RefSeq - XM_017012198
RefSeq Peptide - NP_001008396
RefSeq Peptide - NP_001305165
RefSeq Peptide - NP_001305166
swissprot - C9JXA7
swissprot - A0A087WXQ3
swissprot - A0A087WWR0
swissprot - A0A087WVU0
swissprot - A0A087WV46
swissprot - A0A087WVK8
swissprot - A0A087WT92
swissprot - Q0VGL1
Ensembl - ENSG00000188186
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q0P3X8ENSDARG00000045542Danio rerio
 Q8CF66ENSMUSG00000050552Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR034601  Ragulator complex protein LAMTOR4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007050 cell cycle arrest TAS
 biological_processGO:0008361 regulation of cell size IMP
 biological_processGO:0016241 regulation of macroautophagy TAS
 biological_processGO:0032008 positive regulation of TOR signaling IEA
 biological_processGO:0061462 protein localization to lysosome IMP
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0071986 Ragulator complex IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0032947 protein-containing complex scaffold activity IDA


Pathways (from Reactome)
Pathway description
Macroautophagy
mTOR signalling
mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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