ENSDARG00000045543


Danio rerio

Features
Gene ID: ENSDARG00000045543
  
Biological name :atp6v1f
  
Synonyms : atp6v1f / ATPase H+ transporting V1 subunit F
  
Possible biological names infered from orthology : ATPase, H+ transporting, lysosomal V1 subunit F / Q16864 / Q9D1K2
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 20049260
Gene end: 20063234
  
Corresponding Affymetrix probe sets: Dr.13658.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000066962
NCBI entrez gene - 436799     See in Manteia.
swissprot - Q6DRK0
ZFIN ID - ZDB-GENE-040718-259
Ensembl - ENSDARG00000045543
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q16864ENSG00000128524Homo sapiens
 Q9D1K2ENSMUSG00000004285Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005772  ATPase, V1 complex, subunit F, eukaryotic
 IPR008218  ATPase, V1 complex, subunit F


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0060036 notochord cell vacuolation IMP
 biological_processGO:0060041 retina development in camera-type eye IMP
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 biological_processGO:1901207 regulation of heart looping IMP
 biological_processGO:1902017 regulation of cilium assembly IMP
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0033180 proton-transporting V-type ATPase, V1 domain IEA
 molecular_functionGO:0042625 ATPase coupled ion transmembrane transporter activity IBA
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism IEA


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle decreased size , abnormal
Kupffers vesicle cilium decreased length , abnormal
Kupffers vesicle cilium decreased amount , abnormal
Show

 ZFA:0000008 brain brain necrotic , abnormal
Show

 ZFA:0000023 forerunner cell group forerunner cell group cell decreased amount , abnormal
forerunner cell group cell proliferation decreased occurrence , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
eye decreased pigmentation , abnormal
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 ZFA:0000112 gut gut hypoplastic , abnormal
gut quality , abnormal
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 ZFA:0000114 heart heart quality , abnormal
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 ZFA:0000123 liver liver hypoplastic , abnormal
liver quality , abnormal
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 ZFA:0000135 notochord notochord vacuole broken , abnormal
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 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium malformed , abnormal
retinal pigmented epithelium physical object quality , abnormal
retinal pigmented epithelium translucent , abnormal
retinal pigmented epithelium quality , abnormal
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 ZFA:0001094 whole organism whole organism decreased pigmentation , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head necrotic , abnormal
head cuboid , abnormal
Show

 ZFA:0001115 trunk trunk unpigmented , abnormal
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 ZFA:0005220 larval melanophore stripe larval melanophore stripe melanocyte translucent , abnormal
Show

 ZFA:0009090 pigment cell pigment cell quality , abnormal
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 ZFA:0009091 melanocyte melanocyte increased size , abnormal
melanocyte malformed , abnormal
melanocyte translucent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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