ENSDARG00000054137


Danio rerio

Features
Gene ID: ENSDARG00000054137
  
Biological name :adgrg6
  
Synonyms : adgrg6 / adhesion G protein-coupled receptor G6
  
Possible biological names infered from orthology : Adhesion G-protein coupled receptor G6 ADGRG6 N-terminal fragment ADGRG6 C-terminal fragment / Q6F3F9 / Q86SQ4
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 37383034
Gene end: 37469640
  
Corresponding Affymetrix probe sets: Dr.1140.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000115692
Ensembl peptide - ENSDARP00000109070
Ensembl peptide - ENSDARP00000127298
Ensembl peptide - ENSDARP00000127369
NCBI entrez gene - 561970     See in Manteia.
RefSeq - NM_001163291
RefSeq Peptide - NP_001156763
swissprot - F1Q7U5
swissprot - E7F1G3
swissprot - U3JAN0
swissprot - U3JAV0
ZFIN ID - ZDB-GENE-041014-357
Ensembl - ENSDARG00000054137
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADGRG6ENSGALG00000013803Gallus gallus
 ADGRG6ENSG00000112414Homo sapiens
 Adgrg6ENSMUSG00000039116Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
adgrg4a / adhesion G protein-coupled receptor G4a / ADGRG4* / B7ZCC9* / Q8IZF6* / adhesion G protein-coupled receptor G4*ENSDARG0000010541625
si:dkey-259j3.5 / ADGRG2* / Q8CJ12* / Q8IZP9* / adhesion G protein-coupled receptor G2*ENSDARG0000008893723
adgrg2a / adhesion G protein-coupled receptor G2a / ADGRG2* / Q8IZP9* / adhesion G protein-coupled receptor G2*ENSDARG0000008813722
adgrg4b / adhesion G protein-coupled receptor G4b / ADGRG4* / B7ZCC9* / Q8IZF6* / adhesion G protein-coupled receptor G4*ENSDARG0000009438618
adgrg11 / adhesion G protein-coupled receptor G11ENSDARG0000004141312
adgrg1 / adhesion G protein-coupled receptor G1ENSDARG0000002722212
CABZ01056052.1ENSDARG000001107489
adgrg3 / adhesion G protein-coupled receptor G3 / Q86Y34*ENSDARG000000747829
CABZ01056051.1ENSDARG000001144655
adgrg7.2 / adhesion G protein-coupled receptor G7, tandem duplicate 2 / ADGRG7* / Q8BM96* / Q96K78* / adhesion G protein-coupled receptor G7*ENSDARG000000710855
adgrg7.1 / adhesion G protein-coupled receptor G7, tandem duplicate 1 / ADGRG7* / Q8BM96* / Q96K78* / adhesion G protein-coupled receptor G7*ENSDARG000000710882


Protein motifs (from Interpro)
Interpro ID Name
 IPR000203  GPS motif
 IPR000832  GPCR, family 2, secretin-like
 IPR000859  CUB domain
 IPR001759  Pentraxin-related
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000114 heart heart lacks all parts of type trabecular layer , abnormal
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 ZFA:0000154 sinus venosus sinus venosus increased accumulation blood , abnormal
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 ZFA:0000175 posterior lateral line nerve posterior lateral line nerve myelin sheath morphology , abnormal
posterior lateral line nerve myelin sheath decreased thickness , abnormal
posterior lateral line nerve decreased thickness , abnormal
posterior lateral line nerve compact myelin absent , abnormal
posterior lateral line nerve decreased amount , abnormal
posterior lateral line nerve sodium channel complex decreased amount , abnormal
posterior lateral line nerve myelination in peripheral nervous system decreased process quality , abnormal
posterior lateral line nerve myelin sheath physical object quality , abnormal
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 ZFA:0000217 inner ear inner ear swollen , abnormal
inner ear increased size , abnormal
inner ear edematous , abnormal
inner ear quality , abnormal
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 ZFA:0000282 sensory system sensory system quality , abnormal
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 ZFA:0000431 semicircular canal semicircular canal disorganized , abnormal
semicircular canal malformed , abnormal
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 ZFA:0000944 posterior lateral line posterior lateral line Schwann cell development decreased process quality , abnormal
posterior lateral line peripheral nervous system myelin formation decreased process quality , abnormal
posterior lateral line peripheral nervous system axon ensheathment arrested , abnormal
posterior lateral line myelination of posterior lateral line nerve axons arrested , abnormal
posterior lateral line myelination in peripheral nervous system arrested , abnormal
posterior lateral line myelination in peripheral nervous system decreased occurrence , abnormal
posterior lateral line myelination of posterior lateral line nerve axons decreased occurrence , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0001189 vertebra vertebra mineralized , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel morphology , abnormal
intersegmental vessel has fewer parts of type blood vessel endothelial cell , abnormal
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 ZFA:0001319 myocardium myocardium mitochondrion elongated , abnormal
myocardium mitochondrial crista increased branchiness , abnormal
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 ZFA:0001439 anatomical system anatomical system quality , abnormal
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 ZFA:0001715 otic vesicle protrusion otic vesicle protrusion disorganized , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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