ENSDARG00000055225


Danio rerio

Features
Gene ID: ENSDARG00000055225
  
Biological name :dock8
  
Synonyms : dedicator of cytokinesis 8 / dock8
  
Possible biological names infered from orthology : Dedicator of cytokinesis protein 8 / Q8C147 / Q8NF50
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 30325902
Gene end: 30424182
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000113507
Ensembl peptide - ENSDARP00000116729
Ensembl peptide - ENSDARP00000089794
NCBI entrez gene - 403040     See in Manteia.
RefSeq - XM_001920072
RefSeq - XM_009304069
RefSeq - XM_021478460
swissprot - F1QJ79
swissprot - B0V2T6
swissprot - F1RB11
ZFIN ID - ZDB-GENE-060503-743
Ensembl - ENSDARG00000055225
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000035473Gallus gallus
 ENSGALG00000010156Gallus gallus
 DOCK8ENSG00000107099Homo sapiens
 Dock8ENSMUSG00000052085Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dock7 / dedicator of cytokinesis 7 / Q96N67*ENSDARG0000007867555
dock6 / dedicator of cytokinesis 6 / Q96HP0*ENSDARG0000003570653
dock9b / dedicator of cytokinesis 9b / DOCK9* / Q9BZ29* / dedicator of cytokinesis 9* / dedicator of cytokinesis protein 9 isoform 5 *ENSDARG0000001631129
dock10 / dedicator of cytokinesis 10 / Q96BY6*ENSDARG0000007532727
dock11 / dedicator of cytokinesis 11 / A2AF47* / Q5JSL3* / Dedicator of cytokinesis protein 11 *ENSDARG0000006248527
DOCK9 (1 of many) / dedicator of cytokinesis 9 / DOCK9* / Q9BZ29*ENSDARG0000011408627


Protein motifs (from Interpro)
Interpro ID Name
 IPR010703  Dedicator of cytokinesis, C-terminal
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR021816  Dedicator of cytokinesis C/D, N-terminal
 IPR026791  Dedicator of cytokinesis
 IPR027007  DHR-1 domain
 IPR027357  DHR-2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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