ENSDARG00000056102


Danio rerio

Features
Gene ID: ENSDARG00000056102
  
Biological name :uxs1
  
Synonyms : Q6GMI9 / UDP-glucuronate decarboxylase 1 / uxs1
  
Possible biological names infered from orthology : Q8NBZ7 / Q91XL3
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 6255682
Gene end: 6370693
  
Corresponding Affymetrix probe sets: Dr.7218.1.S1_at (Zebrafish Array)   NM_173242_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000072986
Ensembl peptide - ENSDARP00000124615
NCBI entrez gene - 192315     See in Manteia.
RefSeq - NM_173242
RefSeq Peptide - NP_775349
swissprot - F8W2T4
swissprot - Q6GMI9
ZFIN ID - ZDB-GENE-020419-37
Ensembl - ENSDARG00000056102
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UXS1ENSGALG00000016801Gallus gallus
 UXS1ENSG00000115652Homo sapiens
 Uxs1ENSMUSG00000057363Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gale / UDP-galactose-4-epimerase / Q14376* / Q8R059* / Mus musculus galactose-4-epimerase, UDP (Gale), mRNA.*ENSDARG0000000240117


Protein motifs (from Interpro)
Interpro ID Name
 IPR016040  NAD(P)-binding domain
 IPR021761  UDP-glucuronate decarboxylase N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001503 ossification IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0015012 heparan sulfate proteoglycan biosynthetic process IMP
 biological_processGO:0030166 proteoglycan biosynthetic process IMP
 biological_processGO:0030198 extracellular matrix organization IMP
 biological_processGO:0030206 chondroitin sulfate biosynthetic process IMP
 biological_processGO:0033320 UDP-D-xylose biosynthetic process IEA
 biological_processGO:0050650 chondroitin sulfate proteoglycan biosynthetic process IMP
 biological_processGO:0051216 cartilage development IMP
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0048040 UDP-glucuronate decarboxylase activity IBA
 molecular_functionGO:0070403 NAD+ binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton quality , abnormal
Show

 ZFA:0000250 opercle opercle decreased size , abnormal
Show

 ZFA:0000292 surface structure surface structure quality , abnormal
Show

 ZFA:0000561 parasphenoid parasphenoid decreased size , abnormal
Show

 ZFA:0000578 ceratohyal bone ceratohyal bone absent , abnormal
Show

 ZFA:0000672 hyomandibula hyomandibula absent , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism anterior-posterior axis dwarf-like , abnormal
Show

 ZFA:0001114 head head circular , abnormal
head decreased size , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin decreased size , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased length , abnormal
Meckels cartilage anterior side decreased distance ceratohyal cartilage posterior side, abnormal
Meckels cartilage aplastic , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton condensed , abnormal
Show

 ZFA:0001239 ceratobranchial 5 bone ceratobranchial 5 bone decreased size , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch decreased size , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage aplastic , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage decreased length , abnormal
ceratohyal cartilage aplastic , abnormal
Show

 ZFA:0001458 cranial cartilage cranial cartilage morphology , abnormal
cranial cartilage deformed , abnormal
cranial cartilage collagen trimer morphology , abnormal
cranial cartilage fibrillar collagen trimer absent , abnormal
cranial cartilage collagen type I trimer decreased amount , abnormal
cranial cartilage collagen type II trimer absent , abnormal
cranial cartilage collagen type VI trimer absent , abnormal
cranial cartilage extracellular matrix composition , abnormal
cranial cartilage extracellular matrix decreased size , abnormal
cranial cartilage extracellular matrix component spatial pattern , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage chondrocyte crowded , abnormal
pharyngeal arch cartilage decreased length , abnormal
pharyngeal arch cartilage increased thickness , abnormal
pharyngeal arch cartilage oriented , abnormal
pharyngeal arch cartilage chondrocyte circular , abnormal
pharyngeal arch cartilage chondrocyte disorganized , abnormal
pharyngeal arch cartilage aplastic , abnormal
Show

 ZFA:0001461 chondrocranium cartilage chondrocranium cartilage aplastic , abnormal
Show

 ZFA:0001501 cartilage element cartilage element morphology , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage aplastic , abnormal
Show

 ZFA:0001630 perichondral bone perichondral bone aplastic , abnormal
Show

 ZFA:0001634 perichondrium perichondrium physical object quality , abnormal
perichondrium aplastic , abnormal
Show

 ZFA:0009084 chondrocyte chondrocyte fibrillar collagen trimer decreased amount , abnormal
chondrocyte extracellular matrix condensed , abnormal
chondrocyte extracellular matrix decreased area , abnormal
chondrocyte disorganized , abnormal
chondrocyte morphology , abnormal
chondrocyte fused with chondrocyte , abnormal
chondrocyte attached to chondrocyte , abnormal
chondrocyte plasma membrane smooth , abnormal
chondrocyte cell projection membrane absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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