ENSMUSG00000057363


Mus musculus

Features
Gene ID: ENSMUSG00000057363
  
Biological name :Uxs1
  
Synonyms : Q91XL3 / UDP-glucuronate decarboxylase 1 / Uxs1
  
Possible biological names infered from orthology : Q8NBZ7
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C1.1
Gene start: 43746966
Gene end: 43827800
  
Corresponding Affymetrix probe sets: 10354258 (MoGene1.0st)   1426275_a_at (Mouse Genome 430 2.0 Array)   1444642_at (Mouse Genome 430 2.0 Array)   1452011_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116719
Ensembl peptide - ENSMUSP00000144114
Ensembl peptide - ENSMUSP00000121869
Ensembl peptide - ENSMUSP00000119939
Ensembl peptide - ENSMUSP00000118468
Ensembl peptide - ENSMUSP00000076259
NCBI entrez gene - 67883     See in Manteia.
MGI - MGI:1915133
RefSeq - XM_006496228
RefSeq - NM_026430
RefSeq - XM_006496227
RefSeq Peptide - NP_080706
swissprot - D3Z411
swissprot - D6RIQ1
swissprot - G5E8H4
swissprot - Q91XL3
swissprot - D3YUF9
swissprot - A0A0J9YUC7
Ensembl - ENSMUSG00000057363
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 uxs1ENSDARG00000056102Danio rerio
 UXS1ENSGALG00000016801Gallus gallus
 UXS1ENSG00000115652Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tgds / Q8VDR7 / dTDP-D-glucose 4,6-dehydratase / O95455* / TDP-glucose 4,6-dehydratase*ENSMUSG0000002213019
Gale / Q8R059 / Mus musculus galactose-4-epimerase, UDP (Gale), mRNA. / Q14376* / UDP-galactose-4-epimerase*ENSMUSG0000002867117


Protein motifs (from Interpro)
Interpro ID Name
 IPR016040  NAD(P)-binding domain
 IPR021761  UDP-glucuronate decarboxylase N-terminal
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0033320 UDP-D-xylose biosynthetic process IEA
 biological_processGO:0051262 protein tetramerization IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0048040 UDP-glucuronate decarboxylase activity IEA
 molecular_functionGO:0070403 NAD+ binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001800 abnormal humoral immune response "abnormal immune function mediated by antibodies" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Oca2p-88H/Oca2p
Genetic Background: involves: 101/H

 MP:0008499 increased IgG1 level "greater than normal immunoglobulin class G1 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-88H/Oca2p
Genetic Background: involves: 101/H

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Oca2p-88H/Oca2p
Genetic Background: involves: 101/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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