Manteia

ENSDARG00000056127

Danio rerio

Features

Gene ID:	ENSDARG00000056127

Biological name :	polr2gl

Synonyms :	polr2gl / polymerase (RNA) II (DNA directed) polypeptide G-like / Q7ZW41

Possible biological names infered from orthology :	DNA-directed RNA polymerase II subunit RPB7 / P62487 / P62488 / POLR2G / RNA polymerase II subunit G

Species:	Danio rerio

Chr. number:	14
Strand:	1
Band:
Gene start:	26715626
Gene end:	26719053

Corresponding Affymetrix probe sets:	Dr.26442.1.S1_at (Zebrafish Array) NM_199669_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000073018 NCBI entrez gene - 324088 See in Manteia. RefSeq - NM_199669 RefSeq Peptide - NP_955963 swissprot - B2GQV3 swissprot - Q7ZW41 ZFIN ID - ZDB-GENE-030131-2808 Ensembl - ENSDARG00000056127

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR003029	S1 domain
IPR005576	RNA polymerase Rpb7, N-terminal
IPR012340	Nucleic acid-binding, OB-fold
IPR022967	RNA-binding domain, S1

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic	IBA
biological_process	GO:0006351	transcription, DNA-templated	IEA
biological_process	GO:0006366	transcription by RNA polymerase II	ISS
biological_process	GO:0006367	transcription initiation from RNA polymerase II promoter	IBA
biological_process	GO:0045948	positive regulation of translational initiation	IBA
biological_process	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	IBA
cellular_component	GO:0000932	P-body	IBA
cellular_component	GO:0005634	nucleus	ISS
cellular_component	GO:0005665	DNA-directed RNA polymerase II, core complex	ISS
molecular_function	GO:0003676	nucleic acid binding	IEA
molecular_function	GO:0003697	single-stranded DNA binding	IBA
molecular_function	GO:0003727	single-stranded RNA binding	IBA
molecular_function	GO:0003899	DNA-directed 5"-3" RNA polymerase activity	IBA
molecular_function	GO:0031369	translation initiation factor binding	IBA

Pathways (from Reactome)

Pathway description

Formation of RNA Pol II elongation complex

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000012	central nervous system	central nervous system necrotic , abnormal	Show
ZFA:0000054	pericardium	pericardium edematous , abnormal	Show
ZFA:0000084	yolk	yolk quality , abnormal yolk morphology , abnormal	Show
ZFA:0000106	extension	extension decreased thickness , abnormal	Show
ZFA:0000107	eye	eye decreased size , abnormal	Show
ZFA:0000396	nervous system	nervous system quality , abnormal	Show
ZFA:0001094	whole organism	whole organism shape , abnormal whole organism viability , abnormal whole organism decreased size , abnormal whole organism lethal (sensu genetics) , abnormal	Show
ZFA:0001114	head	head flat , abnormal head decreased size , abnormal	Show
ZFA:0001115	trunk	trunk decreased thickness , abnormal trunk atrophied , abnormal trunk decreased pigmentation , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr