ENSDARG00000056427


Danio rerio

Features
Gene ID: ENSDARG00000056427
  
Biological name :auts2a
  
Synonyms : autism susceptibility candidate 2a / auts2a / si:dkey-33o22.1
  
Possible biological names infered from orthology : A0A087WPF7 / Autism susceptibility 2 protein homolog / AUTS2 / AUTS2, activator of transcription and developmental regulator / Q8WXX7
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 27182704
Gene end: 27741793
  
Corresponding Affymetrix probe sets: Dr.12778.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000107382
Ensembl peptide - ENSDARP00000156834
Ensembl peptide - ENSDARP00000156015
Ensembl peptide - ENSDARP00000151262
Ensembl peptide - ENSDARP00000145935
Ensembl peptide - ENSDARP00000145745
Ensembl peptide - ENSDARP00000144835
Ensembl peptide - ENSDARP00000123081
Ensembl peptide - ENSDARP00000073379
NCBI entrez gene - 368890     See in Manteia.
swissprot - E7F4D0
swissprot - A0A1X9RK91
swissprot - A0A1X9RK88
swissprot - A0A1X9RK87
swissprot - A0A1X9RK86
swissprot - A0A1X9RK84
swissprot - A0A1X9RK82
swissprot - F1QGA1
swissprot - F1QRM5
ZFIN ID - ZDB-GENE-030616-571
ZFIN ID - ZDB-GENE-091204-221
Ensembl - ENSDARG00000056427
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AUTS2ENSGALG00000001153Gallus gallus
 AUTS2ENSG00000158321Homo sapiens
 Auts2ENSMUSG00000029673Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fbrsl1 / fibrosin-like 1 / Q9HCM7* / fibrosin-1-like protein isoform 3 *ENSDARG0000005823229
auts2b / autism susceptibility candidate 2b / AUTS2* / Q8WXX7* / A0A087WPF7* / Autism susceptibility 2 protein homolog * / AUTS2, activator of transcription and developmental regulator*ENSDARG0000002094628
fbrs / fibrosin / Q8R089* / Q9HAH7* / Probable fibrosin-1 *ENSDARG0000007468826
si:dkey-33o22.1ENSDARG000000876392


Protein motifs (from Interpro)
Interpro ID Name
 IPR023246  Autism susceptibility gene 2 protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0021884 forebrain neuron development IMP
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0070050 neuron cellular homeostasis IMP
 cellular_componentGO:0005623 cell IEA


Pathways (from Reactome)
Pathway description
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord motor neuron decreased amount , abnormal
spinal cord Rohon-Beard neuron decreased amount , abnormal
Show

 ZFA:0000100 cerebellum cerebellum neuron decreased amount , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000108 fin fin decreased size , abnormal
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 ZFA:0000109 forebrain forebrain has fewer parts of type neuron , abnormal
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 ZFA:0000445 optic tectum optic tectum neuron decreased amount , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk decreased size , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased distance ceratohyal cartilage , abnormal
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 ZFA:0009052 motor neuron motor neuron neuron projection decreased size , abnormal
motor neuron neuron projection perpendicular to spinal cord , abnormal
motor neuron axon increased branchiness , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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