ENSDARG00000058203


Danio rerio

Features
Gene ID: ENSDARG00000058203
  
Biological name :smc1al
  
Synonyms : smc1al / structural maintenance of chromosomes 1A, like
  
Possible biological names infered from orthology : Q14683 / Q9CU62 / SMC1A / structural maintenance of chromosomes 1A
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 12840080
Gene end: 12897815
  
Corresponding Affymetrix probe sets: Dr.20020.1.S1_at (Zebrafish Array)   Dr.20020.2.S1_at (Zebrafish Array)   Dr.24771.1.A1_at (Zebrafish Array)   Dr.25173.1.S1_at (Zebrafish Array)   Dr.4407.1.A1_at (Zebrafish Array)   NM_212810_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000075459
Ensembl peptide - ENSDARP00000105036
Ensembl peptide - ENSDARP00000150758
NCBI entrez gene - 403060     See in Manteia.
RefSeq - NM_212810
RefSeq Peptide - NP_997975
swissprot - Q6DRM9
swissprot - Q6NYA8
ZFIN ID - ZDB-GENE-040426-57
Ensembl - ENSDARG00000058203
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SMC1AENSG00000072501Homo sapiens
 Smc1aENSMUSG00000041133Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
smc1a / structural maintenance of chromosomes 1A / Q14683* / Q9CU62*ENSDARG0000005575494
smc1b / structural maintenance of chromosomes 1B / Q8NDV3* / Q920F6*ENSDARG0000001440248


Protein motifs (from Interpro)
Interpro ID Name
 IPR003395  RecF/RecN/SMC, N-terminal
 IPR010935  SMCs flexible hinge
 IPR024704  Structural maintenance of chromosomes protein
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029683  Structural maintenance of chromosomes protein 1A, metazoan


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0007064 mitotic sister chromatid cohesion IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0051276 chromosome organization IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0008278 cohesin complex IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Separation of Sister Chromatids
Establishment of Sister Chromatid Cohesion
Cohesin Loading onto Chromatin
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000084 yolk yolk circular , abnormal
yolk dark grey , abnormal
yolk low brightness , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye decreased size , ameliorated
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism viability , abnormal
whole organism necrotic , abnormal
whole organism lethal (sensu genetics) , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head decreased size , ameliorated
Show

 ZFA:0001115 trunk trunk decreased length , ameliorated
trunk necrotic , abnormal
trunk curved dorsal , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
post-vent region curved , ameliorated
Show

 ZFA:0001458 cranial cartilage cranial cartilage cartilage development disrupted , abnormal
cranial cartilage cartilage development decreased process quality , ameliorated
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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