ENSDARG00000063522


Danio rerio

Features
Gene ID: ENSDARG00000063522
  
Biological name :bbs4
  
Synonyms : Bardet-Biedl syndrome 4 / bbs4
  
Possible biological names infered from orthology : Bardet-Biedl syndrome 4 protein homolog / Q8C1Z7 / Q96RK4
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 2668881
Gene end: 2702935
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000087351
Ensembl peptide - ENSDARP00000104870
NCBI entrez gene - 768303     See in Manteia.
RefSeq - NM_001077466
RefSeq Peptide - NP_001070934
swissprot - F1RBR9
swissprot - E7EXH4
ZFIN ID - ZDB-GENE-060126-2
Ensembl - ENSDARG00000063522
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BBS4ENSGALG00000001798Gallus gallus
 BBS4ENSG00000140463Homo sapiens
 Bbs4ENSMUSG00000025235Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0007368 determination of left/right symmetry IGI
 biological_processGO:0007369 gastrulation IMP
 biological_processGO:0008593 regulation of Notch signaling pathway IMP
 biological_processGO:0032402 melanosome transport IMP
 biological_processGO:0035845 photoreceptor cell outer segment organization IMP
 biological_processGO:0046154 rhodopsin metabolic process IMP
 biological_processGO:0046907 intracellular transport IMP
 biological_processGO:0051877 pigment granule aggregation in cell center IMP
 biological_processGO:0060026 convergent extension IMP
 biological_processGO:0060027 convergent extension involved in gastrulation IMP
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0061371 determination of heart left/right asymmetry IMP
 biological_processGO:0061469 regulation of type B pancreatic cell proliferation IMP
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 biological_processGO:0090245 axis elongation involved in somitogenesis IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005623 cell IEA


Pathways (from Reactome)
Pathway description
BBSome-mediated cargo-targeting to cilium


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle decreased size , abnormal
Show

 ZFA:0000092 axis axis decreased length , abnormal
Show

 ZFA:0000107 eye eye decreased distance eye , abnormal
Show

 ZFA:0000133 neural rod neural rod increased width , abnormal
Show

 ZFA:0000135 notochord notochord kinked , abnormal
notochord increased width , abnormal
Show

 ZFA:0000155 somite somite increased width , abnormal
somite antero-posteriorly flattened , abnormal
somite shape , abnormal
somite increased length , abnormal
somite amorphous , abnormal
somite decreased thickness , abnormal
somite elongated , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
whole organism increased curvature , abnormal
whole organism dorsal side decreased thickness , abnormal
whole organism decreased length , abnormal
Show

 ZFA:0001117 post-vent region post-vent region morphology , abnormal
Show

 ZFA:0001211 presumptive rhombomere 5 presumptive rhombomere 5 decreased distance somite 1 , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton decreased length , abnormal
mandibular arch skeleton increased width , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas decreased area , abnormal
Show

 ZFA:0001390 pancreatic bud pancreatic bud decreased amount , abnormal
Show

 ZFA:0001462 somite border somite border amorphous , abnormal
Show

 ZFA:0001465 photoreceptor inner segment layer photoreceptor inner segment layer structure , abnormal
Show

 ZFA:0005290 proximal convoluted tubule proximal convoluted tubule decreased area , abnormal
Show

 ZFA:0005743 pancreatic D cell pancreatic D cell decreased amount , abnormal
Show

 ZFA:0009000 cell cell detached from neural tube , abnormal
Show

 ZFA:0009102 pancreatic B cell pancreatic B cell increased amount , abnormal
pancreatic B cell decreased amount , abnormal
pancreatic B cell increased area , abnormal
Show

 ZFA:0009104 pancreatic A cell pancreatic A cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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