ENSDARG00000070623


Danio rerio

Features
Gene ID: ENSDARG00000070623
  
Biological name :med10
  
Synonyms : med10 / mediator complex subunit 10 / Q0VIA1
  
Possible biological names infered from orthology : Mediator of RNA polymerase II transcription subunit 10 / Q9BTT4 / Q9CXU0
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 27970292
Gene end: 27974151
  
Corresponding Affymetrix probe sets: Dr.16321.1.S1_at (Zebrafish Array)   Dr.16321.2.S1_at (Zebrafish Array)   Dr.16321.2.S1_a_at (Zebrafish Array)   NM_001017699_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000094663
Ensembl peptide - ENSDARP00000116070
NCBI entrez gene - 550394     See in Manteia.
RefSeq - NM_001017699
RefSeq Peptide - NP_001017699
swissprot - Q0VIA1
ZFIN ID - ZDB-GENE-070117-2423
Ensembl - ENSDARG00000070623
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MED10ENSGALG00000028336Gallus gallus
 MED10ENSG00000133398Homo sapiens
 Med10ENSMUSG00000021598Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019145  Mediator complex, subunit Med10


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0036302 atrioventricular canal development IMP
 biological_processGO:1905072 cardiac jelly development IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016592 mediator complex IEA
 cellular_componentGO:0070847 core mediator complex IBA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood quality , abnormal
Show

 ZFA:0000009 cardiac ventricle cardiac ventricle spatial pattern , abnormal
cardiac ventricle increased distribution , abnormal
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 ZFA:0000114 heart heart malformed , abnormal
heart contractility , abnormal
heart quality , abnormal
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 ZFA:0000135 notochord notochord broken , abnormal
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 ZFA:0000471 atrium atrium spatial pattern , abnormal
atrium increased distribution , abnormal
Show

 ZFA:0001117 post-vent region post-vent region increased amount , abnormal
post-vent region decreased length , abnormal
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 ZFA:0001161 pectoral fin pectoral fin physical object quality , abnormal
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 ZFA:0001315 atrioventricular canal atrioventricular canal absent , abnormal
atrioventricular canal mislocalised , abnormal
atrioventricular canal endocardial cushion absent , abnormal
Show

 ZFA:0001317 endocardial cushion endocardial cushion absent , abnormal
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 ZFA:0001318 cardiac jelly cardiac jelly decreased amount , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0005073 atrioventricular ring atrioventricular ring morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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