ENSG00000133398


Homo sapiens

Features
Gene ID: ENSG00000133398
  
Biological name :MED10
  
Synonyms : MED10 / mediator complex subunit 10 / Q9BTT4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: p15.31
Gene start: 6371881
Gene end: 6378594
  
Corresponding Affymetrix probe sets: 223247_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000255764
NCBI entrez gene - 84246     See in Manteia.
OMIM - 612382
RefSeq - NM_032286
RefSeq Peptide - NP_115662
swissprot - Q9BTT4
Ensembl - ENSG00000133398
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 med10ENSDARG00000070623Danio rerio
 MED10ENSGALG00000028336Gallus gallus
 Med10ENSMUSG00000021598Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019145  Mediator complex, subunit Med10


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016592 mediator complex IEA
 cellular_componentGO:0070847 core mediator complex IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
PPARA activates gene expression
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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