ENSDARG00000070961


Danio rerio

Features
Gene ID: ENSDARG00000070961
  
Biological name :lepr
  
Synonyms : lepr / leptin receptor
  
Possible biological names infered from orthology : P48356 / P48357
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 31184058
Gene end: 31233696
  
Corresponding Affymetrix probe sets: Dr.17784.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000095387
Ensembl peptide - ENSDARP00000073629
NCBI entrez gene - 567241     See in Manteia.
RefSeq - XM_021476907
RefSeq - XM_021476908
RefSeq Peptide - NP_001296332
swissprot - F1QUB9
swissprot - F1QMA9
ZFIN ID - ZDB-GENE-080104-1
Ensembl - ENSDARG00000070961
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LEPRENSGALG00000011058Gallus gallus
 LEPRENSG00000116678Homo sapiens
 LeprENSMUSG00000057722Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR010457  Immunoglobulin C2-set-like, ligand-binding
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003323 type B pancreatic cell development IMP
 biological_processGO:0007399 nervous system development IMP
 biological_processGO:0009749 response to glucose IMP
 biological_processGO:0033210 leptin-mediated signaling pathway IEA
 biological_processGO:0043010 camera-type eye development IMP
 biological_processGO:0048839 inner ear development IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0038021 leptin receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000006 ball ball increased circumference , abnormal
Show

 ZFA:0000008 brain brain dorsal region physical object quality , abnormal
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 ZFA:0000024 retinal ganglion cell layer retinal ganglion cell layer decreased size , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000140 pancreas pancreas has extra parts of type pancreatic B cell , abnormal
pancreas has normal numbers of parts of type pancreatic B cell , ameliorated
Show

 ZFA:0000431 semicircular canal semicircular canal hypoplastic , abnormal
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 ZFA:0000435 cranial nerve II cranial nerve II decreased thickness , abnormal
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 ZFA:0001094 whole organism whole organism decreased size , abnormal
whole organism increased amount , abnormal
whole organism glucose increased amount , abnormal
whole organism increased weight , abnormal
whole organism decreased amount , abnormal
Show

 ZFA:0001115 trunk trunk kinked , abnormal
Show

 ZFA:0001117 post-vent region post-vent region kinked , abnormal
Show

 ZFA:0001617 otolith otolith decreased size , abnormal
Show

 ZFA:0009247 secondary motor neuron secondary motor neuron axon branchiness , abnormal
Show

 ZFA:0009280 Muller cell Muller cell cell proliferation decreased process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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