ENSDARG00000071004


Danio rerio

Features
Gene ID: ENSDARG00000071004
  
Biological name :abhd12
  
Synonyms : abhd12 / abhydrolase domain containing 12 / Q08C93
  
Possible biological names infered from orthology : Q8N2K0 / Q99LR1
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 21154576
Gene end: 21200406
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000095479
Ensembl peptide - ENSDARP00000129468
NCBI entrez gene - 767657     See in Manteia.
swissprot - Q08C93
swissprot - X1WGV9
ZFIN ID - ZDB-GENE-060929-268
Ensembl - ENSDARG00000071004
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ABHD12ENSGALG00000008525Gallus gallus
 ABHD12ENSG00000100997Homo sapiens
 Abhd12ENSMUSG00000032046Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:ch211-117n7.7 / Q7Z5M8* / ABHD12B* / abhydrolase domain containing 12B*ENSDARG0000006982836
si:ch211-117n7.6 / Q7Z5M8* / ABHD12B* / abhydrolase domain containing 12B*ENSDARG0000009207134


Protein motifs (from Interpro)
Interpro ID Name
 IPR000073  Alpha/beta hydrolase fold-1
 IPR026605  Monoacylglycerol lipase protein ABHD12
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010842 retina layer formation IMP
 biological_processGO:0036269 swimming behavior IMP
 biological_processGO:0042552 myelination IMP
 biological_processGO:0043010 camera-type eye development IMP
 biological_processGO:0046464 acylglycerol catabolic process ISS
 biological_processGO:0048899 anterior lateral line development IMP
 biological_processGO:0048919 posterior lateral line neuromast development IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0047372 acylglycerol lipase activity ISS


Pathways (from Reactome)
Pathway description
Arachidonate production from DAG


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system glial cell absent , abnormal
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 ZFA:0000024 retinal ganglion cell layer retinal ganglion cell layer patchy , abnormal
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 ZFA:0000035 lens lens opaque , abnormal
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 ZFA:0000075 spinal cord spinal cord decreased amount , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000175 posterior lateral line nerve posterior lateral line nerve myelinating Schwann cell decreased amount , abnormal
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 ZFA:0000543 medial longitudinal fasciculus medial longitudinal fasciculus decreased amount , abnormal
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 ZFA:0000940 posterior lateral line neuromast posterior lateral line neuromast decreased amount , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0001114 head head decreased length , abnormal
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 ZFA:0001117 post-vent region post-vent region curved dorsal , abnormal
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 ZFA:0001329 retinal inner plexiform layer retinal inner plexiform layer circular , abnormal
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 ZFA:0001472 anterior lateral line neuromast anterior lateral line neuromast decreased amount , abnormal
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 ZFA:0001706 Purkinje cell layer corpus cerebelli Purkinje cell layer corpus cerebelli morphology , abnormal
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 ZFA:0005864 retinotectal tract retinotectal tract morphology , abnormal
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 ZFA:0009063 peripheral neuron peripheral neuron axon guidance process quality , abnormal
peripheral neuron axon morphology , abnormal
peripheral neuron axon shape , abnormal
peripheral neuron axon branchiness , abnormal
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 ZFA:0009073 glial cell glial cell myelination disrupted , abnormal
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 ZFA:0009154 eye photoreceptor cell eye photoreceptor cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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