ENSDARG00000071062


Danio rerio

Features
Gene ID: ENSDARG00000071062
  
Biological name :hps5
  
Synonyms : Hermansky-Pudlak syndrome 5 / hps5
  
Possible biological names infered from orthology : Hermansky-Pudlak syndrome 5 protein homolog / HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 / P59438 / Q9UPZ3
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 3148431
Gene end: 3192405
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000095605
NCBI entrez gene - 100037388     See in Manteia.
RefSeq - NM_001089539
RefSeq Peptide - NP_001083008
swissprot - F6NLH0
ZFIN ID - ZDB-GENE-070410-80
Ensembl - ENSDARG00000071062
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000032502Gallus gallus
 ENSGALG00000006266Gallus gallus
 HPS5ENSG00000110756Homo sapiens
 Hps5ENSMUSG00000014418Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tecpr2 / tectonin beta-propeller repeat containing 2 / O15040* / tectonin beta-propeller repeat-containing protein 2 isoform 2 *ENSDARG0000006083517


Protein motifs (from Interpro)
Interpro ID Name
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR035431  Hermansky-Pudlak syndrome 5 protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030903 notochord development IMP
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0048066 developmental pigmentation IMP
 biological_processGO:0048076 regulation of compound eye pigmentation IMP
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000084 yolk yolk melanocyte decreased amount , abnormal
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 ZFA:0000107 eye eye decreased pigmentation , abnormal
eye decreased size , abnormal
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 ZFA:0000135 notochord notochord structure , abnormal
notochord cell spherical , abnormal
notochord decreased length , abnormal
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 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium melanosome decreased size , abnormal
retinal pigmented epithelium melanosome immature , abnormal
retinal pigmented epithelium melanosome decreased circumference , abnormal
retinal pigmented epithelium melanosome decreased amount , abnormal
retinal pigmented epithelium decreased pigmentation , abnormal
retinal pigmented epithelium melanosome displaced to retinal pigmented epithelium , abnormal
retinal pigmented epithelium melanosome displaced to retina , abnormal
retinal pigmented epithelium melanosome displaced to optic choroid , abnormal
retinal pigmented epithelium melanosome displaced to retinal pigmented epithelium central region, abnormal
retinal pigmented epithelium melanosome displaced to retinal pigmented epithelium dorsal region, abnormal
retinal pigmented epithelium cell projection lacks all parts of type retinal pigmented epithelium melanosome, abnormal
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 ZFA:0001094 whole organism whole organism quality , abnormal
whole organism decreased pigmentation , abnormal
whole organism decreased length , abnormal
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 ZFA:0001114 head head melanocyte decreased amount , abnormal
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 ZFA:0009091 melanocyte melanocyte malformed , abnormal
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 ZFA:0009199 iridophore iridophore absent , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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