ENSDARG00000074121


Danio rerio

Features
Gene ID: ENSDARG00000074121
  
Biological name :dnmbp
  
Synonyms : dnmbp / dynamin binding protein
  
Possible biological names infered from orthology : Q6XZF7
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 31638045
Gene end: 31710590
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000153431
Ensembl peptide - ENSDARP00000155860
Ensembl peptide - ENSDARP00000127353
Ensembl peptide - ENSDARP00000127379
NCBI entrez gene - 100005174     See in Manteia.
RefSeq - XM_001921520
RefSeq - XM_005156345
swissprot - E7F1U2
swissprot - U3JAT4
ZFIN ID - ZDB-GENE-101026-2
Ensembl - ENSDARG00000074121
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000007304Gallus gallus
 DNMBPENSG00000107554Homo sapiens
 DnmbpENSMUSG00000025195Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arhgef38 / Rho guanine nucleotide exchange factor (GEF) 38 / Q80VK6* / Q9NXL2* / Rho guanine nucleotide exchange factor 38*ENSDARG0000007937717
arhgef37 / Rho guanine nucleotide exchange factor (GEF) 37 / A1IGU5* / Rho guanine nucleotide exchange factor 37*ENSDARG0000000246311


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001331  Guanine-nucleotide dissociation stimulator, CDC24, conserved site
 IPR001452  SH3 domain
 IPR004148  BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR035469  Dynamin-binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0007264 small GTPase mediated signal transduction IBA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain hydrocephalic , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000112 gut gut edematous , abnormal
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 ZFA:0000114 heart heart inverted , abnormal
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 ZFA:0000150 pronephric duct pronephric duct cilium disorganized , abnormal
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 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
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 ZFA:0001288 renal glomerulus renal glomerulus disorganized , abnormal
renal glomerulus distended , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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