ENSG00000107554


Homo sapiens

Features
Gene ID: ENSG00000107554
  
Biological name :DNMBP
  
Synonyms : DNMBP / dynamin binding protein / Q6XZF7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q24.2
Gene start: 99875577
Gene end: 100009919
  
Corresponding Affymetrix probe sets: 1562969_at (Human Genome U133 Plus 2.0 Array)   212838_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443657
Ensembl peptide - ENSP00000489875
Ensembl peptide - ENSP00000315659
NCBI entrez gene - 23268     See in Manteia.
OMIM - 611282
RefSeq - XM_011539559
RefSeq - NM_001318326
RefSeq - NM_001318327
RefSeq - NM_015221
RefSeq - XM_006717735
RefSeq Peptide - NP_001305255
RefSeq Peptide - NP_001305256
RefSeq Peptide - NP_056036
swissprot - A0A1C7CYY6
swissprot - Q6XZF7
swissprot - A0A1B0GTX1
Ensembl - ENSG00000107554
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnmbpENSDARG00000074121Danio rerio
 ENSGALG00000007304Gallus gallus
 DnmbpENSMUSG00000025195Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NXL2 / ARHGEF38 / Rho guanine nucleotide exchange factor 38ENSG0000023669918
A1IGU5 / ARHGEF37 / Rho guanine nucleotide exchange factor 37ENSG0000018311112


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001331  Guanine-nucleotide dissociation stimulator, CDC24, conserved site
 IPR001452  SH3 domain
 IPR004148  BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR035469  Dynamin-binding protein
 IPR035817  Dynamin-binding protein, first N-terminal SH3 domain
 IPR035818  Dynamin-binding protein, second N-terminal SH3 domain
 IPR035819  Dynamin-binding protein, third N-terminal SH3 domain
 IPR035820  Dynamin-binding protein, first C-terminal SH3 domain
 IPR035899  Dbl homology (DH) domain superfamily
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IBA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005795 Golgi stack IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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