ENSG00000183111


Homo sapiens

Features
Gene ID: ENSG00000183111
  
Biological name :ARHGEF37
  
Synonyms : A1IGU5 / ARHGEF37 / Rho guanine nucleotide exchange factor 37
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q32
Gene start: 149551947
Gene end: 149634968
  
Corresponding Affymetrix probe sets: 227717_at (Human Genome U133 Plus 2.0 Array)   241380_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328083
Ensembl peptide - ENSP00000425621
NCBI entrez gene - 389337     See in Manteia.
RefSeq - XM_017009461
RefSeq - XM_006714784
RefSeq - XM_011537642
RefSeq - XM_017009460
RefSeq - NM_001001669
RefSeq - XM_005268447
RefSeq - XM_005268448
RefSeq Peptide - NP_001001669
swissprot - D6RJH4
swissprot - A1IGU5
Ensembl - ENSG00000183111
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef37ENSDARG00000002463Danio rerio
 ARHGEF37ENSGALG00000039652Gallus gallus
 Arhgef37ENSMUSG00000045094Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NXL2 / ARHGEF38 / Rho guanine nucleotide exchange factor 38ENSG0000023669929
DNMBP / Q6XZF7 / dynamin binding proteinENSG0000010755429


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001452  SH3 domain
 IPR004148  BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR035636  ARHGEF37, SH3 domain 2
 IPR035823  ARHGEF37, first C-terminal SH3 domain
 IPR035899  Dbl homology (DH) domain superfamily
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IBA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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