ENSDARG00000074617


Danio rerio

Features
Gene ID: ENSDARG00000074617
  
Biological name :wfs1b
  
Synonyms : wfs1b / Wolfram syndrome 1b (wolframin)
  
Possible biological names infered from orthology : O76024 / P56695 / WFS1 / wolframin ER transmembrane glycoprotein
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 17329895
Gene end: 17351159
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124957
NCBI entrez gene - 556580     See in Manteia.
swissprot - E7F921
ZFIN ID - ZDB-GENE-050809-19
Ensembl - ENSDARG00000074617
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WFS1ENSGALG00000015529Gallus gallus
 WFS1ENSG00000109501Homo sapiens
 Wfs1ENSMUSG00000039474Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wfs1a / Wolfram syndrome 1a (wolframin) / WFS1* / O76024* / wolframin ER transmembrane glycoprotein*ENSDARG0000006234147


Protein motifs (from Interpro)
Interpro ID Name
 IPR026208  Wolframin
 IPR026209  Wolframin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003323 type B pancreatic cell development IMP
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:0055074 calcium ion homeostasis IEA
 biological_processGO:1990798 pancreas regeneration IMP
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009102 pancreatic B cell pancreatic B cell increased amount , abnormal
pancreatic B cell decreased distribution , abnormal
pancreatic B cell decreased amount , abnormal
pancreatic B cell decreased area , abnormal
pancreatic B cell regeneration decreased rate , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr