ENSDARG00000076965


Danio rerio

Features
Gene ID: ENSDARG00000076965
  
Biological name :cep70
  
Synonyms : centrosomal protein 70 / cep70
  
Possible biological names infered from orthology : Centrosomal protein of 70 kDa / Q6IQY5 / Q8NHQ1
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 12604302
Gene end: 12626207
  
Corresponding Affymetrix probe sets: Dr.21680.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000153271
Ensembl peptide - ENSDARP00000153411
Ensembl peptide - ENSDARP00000104406
NCBI entrez gene - 100136857     See in Manteia.
RefSeq - NM_001114576
RefSeq Peptide - NP_001108048
swissprot - A5WUW9
ZFIN ID - ZDB-GENE-070705-311
Ensembl - ENSDARG00000076965
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CEP70ENSGALG00000012087Gallus gallus
 CEP70ENSG00000114107Homo sapiens
 Cep70ENSMUSG00000056267Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0060287 epithelial cilium movement involved in determination of left/right asymmetry IMP
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IEA
 cellular_componentGO:0005813 centrosome IEA
 molecular_functionGO:0043015 gamma-tubulin binding IEA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000084 yolk yolk protruding , abnormal
Show

 ZFA:0000123 liver liver inverted , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct cilium decreased length , abnormal
pronephric duct increased size , abnormal
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 ZFA:0000559 otolith organ otolith organ has extra parts of type otolith , abnormal
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 ZFA:0000938 central canal central canal cilium decreased length , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism curved ventral , abnormal
Show

 ZFA:0001360 parapineal organ parapineal organ inverted , abnormal
Show

 ZFA:0001617 otolith otolith mislocalised , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr