ENSG00000114107


Homo sapiens

Features
Gene ID: ENSG00000114107
  
Biological name :CEP70
  
Synonyms : centrosomal protein 70 / CEP70 / Q8NHQ1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q22.3
Gene start: 138494344
Gene end: 138594538
  
Corresponding Affymetrix probe sets: 1554488_at (Human Genome U133 Plus 2.0 Array)   1554489_a_at (Human Genome U133 Plus 2.0 Array)   219036_at (Human Genome U133 Plus 2.0 Array)   224150_s_at (Human Genome U133 Plus 2.0 Array)   238154_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418131
Ensembl peptide - ENSP00000417821
Ensembl peptide - ENSP00000418552
Ensembl peptide - ENSP00000419833
Ensembl peptide - ENSP00000419817
Ensembl peptide - ENSP00000419743
Ensembl peptide - ENSP00000419231
Ensembl peptide - ENSP00000418878
Ensembl peptide - ENSP00000264982
Ensembl peptide - ENSP00000417465
Ensembl peptide - ENSP00000417819
NCBI entrez gene - 80321     See in Manteia.
OMIM - 614310
RefSeq - XM_017007284
RefSeq - NM_024491
RefSeq - XM_005247805
RefSeq - XM_011513209
RefSeq - XM_017007270
RefSeq - XM_017007271
RefSeq - XM_017007272
RefSeq - XM_017007273
RefSeq - XM_017007274
RefSeq - XM_017007275
RefSeq - XM_017007276
RefSeq - XM_017007277
RefSeq - XM_017007278
RefSeq - XM_017007279
RefSeq - XM_017007280
RefSeq - XM_017007282
RefSeq - XM_017007283
RefSeq - NM_001288964
RefSeq - NM_001288965
RefSeq - NM_001288966
RefSeq - NM_001288967
RefSeq - NM_001320598
RefSeq - NM_001320599
RefSeq - NM_001320600
RefSeq Peptide - NP_001275894
RefSeq Peptide - NP_001275895
RefSeq Peptide - NP_001275896
RefSeq Peptide - NP_001307527
RefSeq Peptide - NP_001307528
RefSeq Peptide - NP_001307529
RefSeq Peptide - NP_077817
RefSeq Peptide - NP_001275893
swissprot - C9JZ04
swissprot - C9J966
swissprot - C9J710
swissprot - C9J0F4
swissprot - B7Z2D2
swissprot - H7C4Y6
swissprot - Q8NHQ1
swissprot - A0A140VJG2
Ensembl - ENSG00000114107
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cep70ENSDARG00000076965Danio rerio
 CEP70ENSGALG00000012087Gallus gallus
 Cep70ENSMUSG00000056267Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle TAS
 biological_processGO:0060271 cilium assembly IEA
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IEA
 biological_processGO:0097711 ciliary basal body-plasma membrane docking TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043015 gamma-tubulin binding IEA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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