ENSDARG00000077039


Danio rerio

Features
Gene ID: ENSDARG00000077039
  
Biological name :esama
  
Synonyms : endothelial cell adhesion molecule a / esama
  
Possible biological names infered from orthology : endothelial cell adhesion molecule / Endothelial cell-selective adhesion molecule / ESAM / Q925F2 / Q96AP7
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 31646020
Gene end: 31726486
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000101535
swissprot - F1RB07
ZFIN ID - ZDB-GENE-090629-1
Ensembl - ENSDARG00000077039
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ESAMENSGALG00000032943Gallus gallus
 ESAMENSG00000149564Homo sapiens
 EsamENSMUSG00000001946Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
esamb / endothelial cell adhesion molecule b / ESAM* / Q96AP7* / Q925F2* / endothelial cell adhesion molecule* / Endothelial cell-selective adhesion molecule *ENSDARG0000007663953
igsf11 / immunoglobulin superfamily member 11 / P0C673* / Q5DX21*ENSDARG0000010978328
cxadr / Q90Y50 / CXADR, Ig-like cell adhesion molecule / Gm1123* / P78310* / P97792* / Coxsackievirus and adenovirus receptor homolog *ENSDARG0000004365822
BX927333.1 / CLMP* / Q9H6B4* / CXADR like membrane protein*ENSDARG0000011693721
zgc:165604ENSDARG0000002124119
vsig8b / V-set and immunoglobulin domain containing 8b / VSIG8* / P0DPA2* / Q6P3A4* / V-set and immunoglobulin domain containing 8*ENSDARG0000001368518
vsig8a / V-set and immunoglobulin domain containing 8a / VSIG8* / P0DPA2* / V-set and immunoglobulin domain containing 8*ENSDARG0000005405017
si:zfos-1011f11.1 / GPA33* / Q99795* / glycoprotein A33* / glycoprotein A33 (transmembrane)*ENSDARG0000010022316
gpa33 / glycoprotein A33 (transmembrane) / Q99795* / glycoprotein A33*ENSDARG0000004089812
CABZ01039304.1 / CLMP* / Q9H6B4* / CXADR like membrane protein*ENSDARG000001164876


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0070527 platelet aggregation IMP
 biological_processGO:0120078 cell adhesion involved in sprouting angiogenesis IGI
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000011 caudal artery caudal artery increased accumulation thrombocyte , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel disconnected , abnormal
intersegmental vessel mislocalised , abnormal
intersegmental vessel disconnected , exacerbated
intersegmental vessel basal plasma membrane mislocalised , abnormal
intersegmental vessel occluding junction spatial pattern , abnormal
intersegmental vessel occluding junction disconnected , abnormal
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 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel blood vessel development delayed , abnormal
dorsal longitudinal anastomotic vessel blood vessel development delayed , exacerbated
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 ZFA:0005604 angiogenic sprout angiogenic sprout endothelial tip cell detached from angiogenic sprout , exacerbated
angiogenic sprout has extra parts of type endothelial cell filopodium, abnormal
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 ZFA:0009303 endothelial tip cell endothelial tip cell cell adhesion decreased efficacy , exacerbated
endothelial tip cell actin filament bundle of filopodium decreased amount , abnormal
endothelial tip cell aggregated , abnormal
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 ZFA:0009323 thrombocyte thrombocyte aggregated , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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