ENSG00000149564


Homo sapiens

Features
Gene ID: ENSG00000149564
  
Biological name :ESAM
  
Synonyms : endothelial cell adhesion molecule / ESAM / Q96AP7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q24.2
Gene start: 124752583
Gene end: 124762290
  
Corresponding Affymetrix probe sets: 225369_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000406689
Ensembl peptide - ENSP00000415893
Ensembl peptide - ENSP00000278927
Ensembl peptide - ENSP00000389235
NCBI entrez gene - 90952     See in Manteia.
OMIM - 614281
RefSeq - NM_138961
RefSeq - XM_011543060
RefSeq Peptide - NP_620411
swissprot - C9JIE7
swissprot - F8WDW9
swissprot - Q96AP7
Ensembl - ENSG00000149564
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 esamaENSDARG00000077039Danio rerio
 esambENSDARG00000076639Danio rerio
 ESAMENSGALG00000032943Gallus gallus
 EsamENSMUSG00000001946Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IGSF11 / Q5DX21 / immunoglobulin superfamily member 11ENSG0000014484729
VSIG2 / Q96IQ7 / V-set and immunoglobulin domain containing 2ENSG0000001910226
CXADR / P78310 / CXADR, Ig-like cell adhesion moleculeENSG0000015463924
CLMP / Q9H6B4 / CXADR like membrane proteinENSG0000016625024
VSIG8 / P0DPA2 / V-set and immunoglobulin domain containing 8ENSG0000024328424
VSIG1 / Q86XK7 / V-set and immunoglobulin domain containing 1ENSG0000010184220
GPA33 / Q99795 / glycoprotein A33ENSG0000014316719


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR021157  Cytochrome c1, transmembrane anchor, C-terminal
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0070062 extracellular exosome HDA


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000110876 Q14242 / SELPLG / selectin P ligand  / complex / reaction






 

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