ENSG00000110876


Homo sapiens

Features
Gene ID: ENSG00000110876
  
Biological name :SELPLG
  
Synonyms : Q14242 / selectin P ligand / SELPLG
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.11
Gene start: 108622277
Gene end: 108633959
  
Corresponding Affymetrix probe sets: 209879_at (Human Genome U133 Plus 2.0 Array)   209880_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000373614
Ensembl peptide - ENSP00000447752
Ensembl peptide - ENSP00000228463
NCBI entrez gene - 6404     See in Manteia.
OMIM - 600738
RefSeq - NM_001206609
RefSeq - NM_003006
RefSeq Peptide - NP_001193538
RefSeq Peptide - NP_002997
swissprot - A0A0C4DFY0
swissprot - Q14242
Ensembl - ENSG00000110876
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 selplgENSDARG00000105023Danio rerio
 SelplgENSMUSG00000048163Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026195  P-selectin glycoprotein ligand 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0050900 leukocyte migration IDA
 biological_processGO:0050901 leukocyte tethering or rolling IDA
 biological_processGO:0050902 leukocyte adhesive activation ISS
 biological_processGO:0071354 cellular response to interleukin-6 IDA
 cellular_componentGO:0001931 uropod IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0044853 plasma membrane raft IDA
 molecular_functionGO:0001618 virus receptor activity IEA
 molecular_functionGO:0005102 signaling receptor binding NAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000090863 GLG1 / Q92896 / golgi glycoprotein 1  / complex / reaction
 ENSG00000007908 SELE / P16581 / selectin E  / complex / reaction
 ENSG00000149564 ESAM / Q96AP7 / endothelial cell adhesion molecule  / complex / reaction
 ENSG00000197471 SPN / P16150 / sialophorin  / reaction / complex
 ENSG00000188404 SELL / P14151 / selectin L  / reaction / complex
 ENSG00000110876 Q14242 / SELPLG / selectin P ligand  / complex / reaction
 ENSG00000026508 CD44 / P16070 / CD44 molecule (Indian blood group)  / complex / reaction
 ENSG00000174175 SELP / P16109 / selectin P  / complex / reaction






 

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